C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cell division cycle 34
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000099804 CDC34 9606 + 19:531712-542092 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000215574 CDC34-001 531712-542087 protein_coding
  ENST00000586283 CDC34-005 532031-542092 protein_coding
  ENST00000586788 CDC34-002 531769-536715 retained_intron
  ENST00000593036 CDC34-006 541216-541658 processed_transcript
  ENST00000606065 CDC34-004 535837-541556 protein_coding
  ENST00000606400 CDC34-007 536952-542041 retained_intron
  ENST00000607527 CDC34-003 532100-541584 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000215574ENST00000586283ENST00000586788ENST00000593036ENST00000606065ENST00000606400ENST00000607527
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000215574 20.776±0.00 10.052±0.00 0.566±0.00 12.265±2.27 14.349±9.75 29.484±21.32 15.589±12.59 12.893±9.51 28.004±0.00 31.139±28.60 32.614±26.76 25.287±15.55 55.273±5.00 93.457±30.75
ENST00000586283 6.232±0.00 4.272±0.00 3.153±0.00 4.180±0.00 5.494±0.00 N/A 3.396±0.00 2.296±0.00 2.681±0.00 1.270±0.00 3.041±0.00 8.804±0.00 19.079±0.00 N/A
ENST00000586788 N/A N/A 2.357±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000593036 N/A N/A N/A N/A 17.753±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000606065 10.691±0.00 N/A N/A 4.537±0.00 6.816±0.00 N/A 14.173±0.00 N/A N/A 1.907±0.00 N/A 3.718±0.00 N/A N/A
ENST00000606400 N/A 10.014±0.00 N/A 11.140±0.00 N/A N/A N/A N/A N/A N/A N/A 21.077±0.00 30.595±3.56 23.782±0.00
ENST00000607527 N/A N/A N/A 19.901±0.00 N/A N/A N/A N/A N/A N/A N/A 22.840±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_0007DQ CIL_0007DQ_0001 CGP 19:507299-542092
CIL_0001FW CIL_0001FW_0001 CGP 19:531712-549924

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 NAS G1/S transition of mitotic cell cycle
GO:0000209 IDA protein polyubiquitination
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006270 NAS DNA replication initiation
GO:0006464 NAS cellular protein modification process
GO:0008152 IEA metabolic process
GO:0016567 IDA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0043951 IDA negative regulation of cAMP-mediated signaling
GO:0070848 IEA response to growth factor
GO:0070936 IDA protein K48-linked ubiquitination
GO:0090261 IEA positive regulation of inclusion body assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012627 cdc34b cell division cycle 34 homolog (S. cerevisiae) b protein_coding Danio_rerio
ENSDARG00000069708 cdc34a cell division cycle 34 homolog (S. cerevisiae) a protein_coding Danio_rerio
ENSMUSG00000020307 Cdc34 cell division cycle 34 protein_coding Mus_musculus

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