C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gamma-glutamyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100031 GGT1 9606 + 22:24583750-24629005 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000248923 GGT1-005 24583750-24628968 protein_coding
  ENST00000400380 GGT1-001 24603216-24629001 protein_coding
  ENST00000400382 GGT1-002 24603201-24629002 protein_coding
  ENST00000401885 GGT1-025 24627180-24628996 protein_coding
  ENST00000403838 GGT1-024 24627255-24629005 protein_coding
  ENST00000404223 GGT1-028 24627408-24628996 protein_coding
  ENST00000404532 GGT1-026 24627252-24628975 protein_coding
  ENST00000404920 GGT1-027 24627444-24628839 protein_coding
  ENST00000411974 GGT1-011 24594814-24615107 protein_coding
  ENST00000412658 GGT1-003 24603147-24628134 protein_coding
  ENST00000412898 GGT1-014 24603215-24614851 protein_coding
  ENST00000419133 GGT1-013 24603198-24620468 protein_coding
  ENST00000425895 GGT1-006 24609462-24628996 nonsense_mediated_decay
  ENST00000428855 GGT1-020 24607664-24615125 protein_coding
  ENST00000430289 GGT1-023 24603235-24615071 protein_coding
  ENST00000432867 GGT1-017 24607639-24615078 protein_coding
  ENST00000438643 GGT1-019 24603213-24611192 protein_coding
  ENST00000445029 GGT1-012 24603184-24614814 protein_coding
  ENST00000447416 GGT1-016 24607621-24615125 protein_coding
  ENST00000451366 GGT1-018 24607659-24615093 protein_coding
  ENST00000452551 GGT1-004 24603213-24615127 protein_coding
  ENST00000455483 GGT1-015 24603217-24614904 protein_coding
  ENST00000456869 GGT1-010 24594811-24611171 protein_coding
  ENST00000466310 GGT1-009 24620408-24628976 processed_transcript
  ENST00000474191 GGT1-022 24610366-24615972 processed_transcript
  ENST00000487766 GGT1-021 24614862-24620833 retained_intron
  ENST00000490087 GGT1-030 24627876-24628976 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderOvaryENST00000248923ENST00000412658
Transcript ID Bladder Ovary
ENST00000248923 N/A 22.791±0.00
ENST00000412658 6.899±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YG CIL_0006YG_0002 CGP 22:24540423-24609980
CIL_0006ZW CIL_0006ZW_0003 CGP 22:24583750-24629005

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002682 ISS regulation of immune system process
GO:0003840 IEA:TAS gamma-glutamyltransferase activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005886 IDA plasma membrane
GO:0006508 IEA proteolysis
GO:0006520 TAS cellular amino acid metabolic process
GO:0006536 IDA glutamate metabolic process
GO:0006691 TAS leukotriene metabolic process
GO:0006749 IEA:TAS glutathione metabolic process
GO:0006750 ISS glutathione biosynthetic process
GO:0006751 IDA glutathione catabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0007283 ISS spermatogenesis
GO:0016021 IEA integral component of membrane
GO:0019344 ISS cysteine biosynthetic process
GO:0019369 TAS arachidonic acid metabolic process
GO:0019370 IMP leukotriene biosynthetic process
GO:0031362 TAS anchored component of external side of plasma membrane
GO:0031638 IDA zymogen activation
GO:0036374 IDA glutathione hydrolase activity
GO:0044281 TAS small molecule metabolic process
GO:0050727 ISS regulation of inflammatory response
GO:0070062 IDA extracellular vesicular exosome
GO:1901687 TAS glutathione derivative biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018342 ggt1b gamma-glutamyltransferase 1b protein_coding Danio_rerio
ENSDARG00000023526 ggt1a gamma-glutamyltransferase 1a protein_coding Danio_rerio
ENSDARG00000075055 ggt1l2.1 gamma-glutamyltransferase 1 like 2.1 protein_coding Danio_rerio
ENSDARG00000087054 ggt1l2.2 gamma-glutamyltransferase 1 like 2.2 protein_coding Danio_rerio
ENSDARG00000087063 si:ch73-236c18.3 si:ch73-236c18.3 protein_coding Danio_rerio
ENSDARG00000092350 si:dkey-222h21.12 si:dkey-222h21.12 protein_coding Danio_rerio
ENSMUSG00000006345 Ggt1 gamma-glutamyltransferase 1 protein_coding Mus_musculus

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