C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gamma-glutamyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006345 Ggt1 10090 + 10:75561604-75586200 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006508 Ggt1-002 75573448-75586182 protein_coding
  ENSMUST00000124259 Ggt1-013 75571531-75579360 protein_coding
  ENSMUST00000125770 Ggt1-007 75568657-75576054 protein_coding
  ENSMUST00000128886 Ggt1-011 75568662-75576302 protein_coding
  ENSMUST00000129020 Ggt1-016 75576076-75584903 protein_coding
  ENSMUST00000129232 Ggt1-019 75566293-75578917 protein_coding
  ENSMUST00000131565 Ggt1-010 75568641-75576302 protein_coding
  ENSMUST00000134503 Ggt1-001 75568656-75586200 protein_coding
  ENSMUST00000139459 Ggt1-014 75573886-75579383 protein_coding
  ENSMUST00000140219 Ggt1-005 75561655-75576302 protein_coding
  ENSMUST00000141062 Ggt1-020 75564148-75574326 protein_coding
  ENSMUST00000143226 Ggt1-012 75571526-75578920 protein_coding
  ENSMUST00000143792 Ggt1-006 75566298-75579365 protein_coding
  ENSMUST00000145079 Ggt1-004 75561604-75576255 protein_coding
  ENSMUST00000145928 Ggt1-008 75568634-75579282 protein_coding
  ENSMUST00000148447 Ggt1-015 75571570-75581433 processed_transcript
  ENSMUST00000151212 Ggt1-009 75568674-75575969 protein_coding
  ENSMUST00000152657 Ggt1-003 75564155-75576255 protein_coding
  ENSMUST00000155186 Ggt1-018 75581370-75586158 protein_coding
  ENSMUST00000156487 Ggt1-017 75585105-75586191 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006508ENSMUST00000125770ENSMUST00000128886ENSMUST00000129020ENSMUST00000129232ENSMUST00000131565ENSMUST00000134503ENSMUST00000139459ENSMUST00000140219ENSMUST00000141062ENSMUST00000145079ENSMUST00000148447ENSMUST00000155186ENSMUST00000156487
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006508 N/A N/A N/A 0.222±0.00 N/A N/A N/A 45.222±3.57 0.040±0.03 N/A N/A 0.742±0.25 N/A N/A
ENSMUST00000125770 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.588±0.00 N/A N/A
ENSMUST00000128886 N/A N/A N/A N/A N/A N/A N/A N/A 0.161±0.00 N/A N/A N/A N/A N/A
ENSMUST00000129020 0.055±0.00 0.064±0.00 N/A 1.236±0.00 N/A N/A 0.047±0.00 N/A N/A N/A 0.122±0.04 0.826±0.25 11.753±7.88 0.336±0.05
ENSMUST00000129232 N/A 0.177±0.07 N/A N/A N/A N/A N/A N/A N/A N/A 0.081±0.00 N/A N/A N/A
ENSMUST00000131565 N/A N/A N/A N/A N/A N/A 0.063±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000134503 0.062±0.02 N/A 0.161±0.00 0.490±0.22 4.151±1.84 0.928±0.18 N/A 230.721±19.82 6.611±7.64 0.746±0.28 N/A 0.311±0.00 6.867±4.13 0.401±0.23
ENSMUST00000139459 N/A N/A N/A N/A N/A N/A 0.039±0.00 N/A 0.114±0.05 N/A 0.031±0.00 0.370±0.00 N/A N/A
ENSMUST00000140219 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.367±0.00 N/A N/A
ENSMUST00000141062 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.054±0.00 N/A N/A N/A
ENSMUST00000145079 N/A N/A N/A N/A N/A N/A N/A N/A 0.111±0.00 N/A N/A 0.617±0.00 N/A N/A
ENSMUST00000148447 0.130±0.00 N/A N/A 0.948±0.00 N/A N/A N/A N/A N/A N/A 0.182±0.02 N/A 15.668±7.25 N/A
ENSMUST00000155186 N/A 0.072±0.00 N/A N/A N/A N/A 0.043±0.00 N/A 0.118±0.00 N/A 0.049±0.00 0.835±0.14 N/A N/A
ENSMUST00000156487 0.048±0.00 0.070±0.00 N/A 1.362±0.00 N/A N/A 0.064±0.02 N/A 0.213±0.00 N/A N/A 0.589±0.10 11.759±9.54 0.953±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002682 IMP regulation of immune system process
GO:0003840 TAS:ISS gamma-glutamyltransferase activity
GO:0005886 ISS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006508 IEA proteolysis
GO:0006536 ISS glutamate metabolic process
GO:0006749 TAS glutathione metabolic process
GO:0006750 IMP glutathione biosynthetic process
GO:0006751 ISS glutathione catabolic process
GO:0007283 IMP spermatogenesis
GO:0019344 IMP cysteine biosynthetic process
GO:0031638 ISS zymogen activation
GO:0031988 IDA membrane-bounded vesicle
GO:0036374 ISS glutathione hydrolase activity
GO:0050727 IMP regulation of inflammatory response
GO:0060427 TAS lung connective tissue development
GO:0071260 TAS cellular response to mechanical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018342 ggt1b gamma-glutamyltransferase 1b protein_coding Danio_rerio
ENSDARG00000023526 ggt1a gamma-glutamyltransferase 1a protein_coding Danio_rerio
ENSDARG00000075055 ggt1l2.1 gamma-glutamyltransferase 1 like 2.1 protein_coding Danio_rerio
ENSDARG00000087054 ggt1l2.2 gamma-glutamyltransferase 1 like 2.2 protein_coding Danio_rerio
ENSDARG00000087063 si:ch73-236c18.3 si:ch73-236c18.3 protein_coding Danio_rerio
ENSDARG00000092350 si:dkey-222h21.12 si:dkey-222h21.12 protein_coding Danio_rerio
ENSG00000100031 GGT1 gamma-glutamyltransferase 1 protein_coding Homo_sapiens
ENSG00000100121 GGTLC2 gamma-glutamyltransferase light chain 2 protein_coding Homo_sapiens
ENSG00000133475 GGT2 gamma-glutamyltransferase 2 protein_coding Homo_sapiens
ENSG00000149435 GGTLC1 gamma-glutamyltransferase light chain 1 protein_coding Homo_sapiens
ENSG00000274252 GGTLC3 gamma-glutamyltransferase light chain 3 protein_coding Homo_sapiens

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