C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acrosin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100312 ACR 9606 + 22:50738196-50745334 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216139 ACR-001 50738196-50745334 protein_coding
  ENST00000527761 ACR-004 50744144-50744910 processed_transcript
  ENST00000529621 ACR-003 50738230-50740757 protein_coding
  ENST00000533930 ACR-002 50738196-50740359 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216139ENST00000527761ENST00000529621ENST00000533930
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216139 0.466±0.00 0.564±0.00 0.180±0.00 0.198±0.00 0.114±0.00 0.106±0.00 0.042±0.00 N/A 0.170±0.00 0.055±0.00 N/A 0.198±0.06 0.098±0.00 33.260±20.47
ENST00000527761 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.311±0.00 0.156±0.06 N/A
ENST00000529621 N/A N/A N/A N/A N/A 0.056±0.00 N/A N/A 0.211±0.13 0.467±0.18 0.052±0.00 0.089±0.03 0.286±0.00 6.646±0.00
ENST00000533930 0.116±0.00 0.426±0.00 N/A 0.443±0.00 0.133±0.00 N/A N/A 0.115±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00066R CIL_00066R_0001 CGP 22:50738196-50783663

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001669 IEA acrosomal vesicle
GO:0002077 NAS acrosome matrix dispersal
GO:0003677 NAS DNA binding
GO:0003824 IEA catalytic activity
GO:0004040 ISS amidase activity
GO:0004252 IDA:IEA serine-type endopeptidase activity
GO:0005507 NAS copper ion binding
GO:0005515 IPI protein binding
GO:0005537 IDA mannose binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005798 IEA Golgi-associated vesicle
GO:0006508 IEA proteolysis
GO:0007190 IDA activation of adenylate cyclase activity
GO:0007338 ISS single fertilization
GO:0007339 IEA binding of sperm to zona pellucida
GO:0007340 IMP acrosome reaction
GO:0007341 IEA penetration of zona pellucida
GO:0008144 ISS drug binding
GO:0008233 IEA peptidase activity
GO:0008270 NAS zinc ion binding
GO:0032504 TAS multicellular organism reproduction
GO:0042806 ISS fucose binding
GO:0043159 TAS acrosomal matrix
GO:0043234 IDA protein complex
GO:0048545 IEA response to steroid hormone

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000093100 tmprss12 transmembrane (C-terminal) protease, serine 12 protein_coding Danio_rerio
ENSMUSG00000022622 Acr acrosin prepropeptide protein_coding Mus_musculus

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