C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TGF-beta activated kinase 1/MAP3K7 binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100324 TAB1 9606 + 22:39399741-39437060 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216160 TAB1-001 39399741-39431882 protein_coding
  ENST00000331454 TAB1-002 39399784-39436823 protein_coding
  ENST00000461775 TAB1-003 39414730-39416796 retained_intron
  ENST00000473491 TAB1-008 39421735-39428134 retained_intron
  ENST00000473613 TAB1-004 39399778-39416849 retained_intron
  ENST00000488859 TAB1-009 39432431-39437060 processed_transcript
  ENST00000490819 TAB1-006 39416744-39417816 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216160ENST00000331454ENST00000473491
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216160 4.830±0.00 10.162±0.00 0.221±0.00 6.340±5.14 4.101±2.78 5.088±0.00 2.754±2.55 2.582±1.15 2.736±2.06 2.738±1.44 3.960±3.34 9.547±6.37 10.384±1.49 9.910±0.21
ENST00000331454 N/A N/A N/A N/A N/A N/A 0.281±0.00 N/A N/A N/A 1.717±0.00 1.465±0.00 N/A N/A
ENST00000473491 N/A N/A N/A N/A N/A N/A N/A 2.558±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000A3 CIL_0000A3_0001 CGP 22:39349925-39437060
CIL_0007AY CIL_0007AY_0002 CGP 22:39399741-39492194

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000185 IEA activation of MAPKKK activity
GO:0000187 TAS activation of MAPK activity
GO:0001701 IEA in utero embryonic development
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003007 IEA heart morphogenesis
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007249 TAS I-kappaB kinase/NF-kappaB signaling
GO:0007254 TAS JNK cascade
GO:0008047 TAS enzyme activator activity
GO:0010008 TAS endosome membrane
GO:0019209 IEA kinase activator activity
GO:0030324 IEA lung development
GO:0032403 IEA protein complex binding
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043234 IEA protein complex
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0045087 TAS innate immune response
GO:0048273 IEA mitogen-activated protein kinase p38 binding
GO:0051092 TAS positive regulation of NF-kappaB transcription factor activity
GO:0051403 TAS stress-activated MAPK cascade
GO:0070423 TAS nucleotide-binding oligomerization domain containing signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036613 tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 protein_coding Danio_rerio
ENSMUSG00000022414 Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 protein_coding Mus_musculus

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