C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (DNA directed), epsilon 2, accessory subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100479 POLE2 9606 - 14:49643555-49688422 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216367 POLE2-001 49643560-49688303 protein_coding
  ENST00000539565 POLE2-002 49643585-49688422 protein_coding
  ENST00000553805 POLE2-008 49679474-49688203 protein_coding
  ENST00000553850 POLE2-004 49653925-49654463 retained_intron
  ENST00000554377 POLE2-011 49650119-49654320 retained_intron
  ENST00000554396 POLE2-012 49650188-49688210 protein_coding
  ENST00000554671 POLE2-007 49643564-49647360 processed_transcript
  ENST00000554851 POLE2-005 49643555-49651484 retained_intron
  ENST00000555724 POLE2-006 49643564-49647360 processed_transcript
  ENST00000556584 POLE2-003 49643586-49688197 processed_transcript
  ENST00000556937 POLE2-010 49643555-49655064 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216367ENST00000539565ENST00000553850ENST00000554377ENST00000554396ENST00000554671ENST00000554851ENST00000556584ENST00000556937
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216367 N/A N/A N/A N/A 1.230±0.00 N/A N/A N/A N/A N/A 0.979±0.81 0.593±0.33 2.120±0.00
ENST00000539565 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.219±0.00 N/A 1.082±0.00
ENST00000553850 N/A N/A N/A N/A N/A 0.835±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000554377 N/A N/A 0.184±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000554396 0.075±0.00 0.781±0.00 0.146±0.01 0.362±0.00 0.056±0.00 0.133±0.08 0.289±0.00 0.293±0.23 0.297±0.00 N/A 1.374±0.61 0.768±0.00 N/A
ENST00000554671 N/A N/A N/A N/A N/A 0.168±0.00 0.471±0.00 N/A 0.189±0.00 N/A N/A N/A N/A
ENST00000554851 0.050±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.181±0.00 N/A 0.483±0.00 N/A
ENST00000556584 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.663±0.63 0.349±0.14 N/A
ENST00000556937 0.068±0.00 N/A 0.244±0.00 N/A 0.398±0.00 N/A N/A 0.781±0.00 0.228±0.00 N/A 1.702±0.74 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006BX CIL_0006BX_0001 CGP 14:49643555-49753152

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 TAS telomere maintenance
GO:0003677 IEA DNA binding
GO:0003887 IEA DNA-directed DNA polymerase activity
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006260 TAS:IEA DNA replication
GO:0006261 IEA DNA-dependent DNA replication
GO:0006270 TAS DNA replication initiation
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006297 TAS nucleotide-excision repair, DNA gap filling
GO:0008622 IDA epsilon DNA polymerase complex
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038664 pole2 polymerase (DNA directed), epsilon 2 protein_coding Danio_rerio
ENSMUSG00000020974 Pole2 polymerase (DNA directed), epsilon 2 (p59 subunit) protein_coding Mus_musculus

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