C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dehydrogenase/reductase (SDR family) member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100867 DHRS2 9606 + 14:23630115-23645639 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000250383 DHRS2-001 23636335-23645639 protein_coding
  ENST00000344777 DHRS2-002 23636373-23645639 protein_coding
  ENST00000432832 DHRS2-003 23630115-23644543 protein_coding
  ENST00000553600 DHRS2-009 23639339-23645295 protein_coding
  ENST00000553896 DHRS2-004 23630115-23642438 processed_transcript
  ENST00000556550 DHRS2-007 23643045-23645639 retained_intron
  ENST00000556701 DHRS2-005 23636367-23645637 retained_intron
  ENST00000556729 DHRS2-006 23638032-23645639 retained_intron
  ENST00000557535 DHRS2-008 23639293-23645639 protein_coding
  ENST00000611765 DHRS2-201 23638816-23645637 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000250383ENST00000344777ENST00000553600ENST00000553896ENST00000556701ENST00000556729ENST00000557535ENST00000611765
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000250383 N/A N/A N/A N/A N/A N/A N/A 7.791±1.76 21.032±12.89 0.833±0.00 2.449±0.00 4.505±4.04 6.005±2.49 3.155±2.59
ENST00000344777 0.017±0.00 N/A N/A 0.123±0.00 N/A 0.388±0.00 0.346±0.00 3.423±0.00 N/A N/A N/A 0.151±0.00 N/A N/A
ENST00000553600 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.357±0.00 N/A N/A N/A N/A
ENST00000553896 N/A N/A 0.106±0.00 N/A N/A N/A N/A N/A N/A 0.716±0.00 N/A N/A N/A N/A
ENST00000556701 0.037±0.00 0.257±0.00 N/A 0.192±0.00 0.056±0.00 0.007±0.00 0.046±0.00 N/A N/A N/A N/A N/A N/A 0.110±0.00
ENST00000556729 N/A N/A N/A N/A N/A 0.062±0.05 0.031±0.00 N/A 4.143±0.00 0.023±0.00 N/A N/A N/A N/A
ENST00000557535 N/A N/A N/A N/A N/A N/A 0.194±0.00 7.939±0.00 N/A 0.187±0.00 N/A 8.686±8.62 2.853±0.09 1.068±0.00
ENST00000611765 N/A N/A N/A 0.301±0.00 N/A N/A N/A N/A N/A N/A N/A 9.580±0.00 2.008±0.28 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090C CIL_00090C_0001 VISTA 14:23078458-23681621
CIL_0009BW CIL_0009BW_0001 VISTA 14:23137378-23739005
CIL_0008Q4 CIL_0008Q4_0001 VISTA 14:23138150-23738498
CIL_0008QH CIL_0008QH_0001 VISTA 14:23142404-23743714
CIL_0001QP CIL_0001QP_0001 CGP 14:23568035-23645639
CIL_0002T7 CIL_0002T7_0001 CGP 14:23630115-23969279

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004090 IDA carbonyl reductase (NADPH) activity
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0008152 IEA metabolic process
GO:0008207 NAS C21-steroid hormone metabolic process
GO:0008285 NAS negative regulation of cell proliferation
GO:0009636 IDA response to toxic substance
GO:0016491 IEA oxidoreductase activity
GO:0034599 IDA cellular response to oxidative stress
GO:0043011 IEP myeloid dendritic cell differentiation
GO:0043066 IMP negative regulation of apoptotic process
GO:0055114 IEA:IDA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021135 DHRS2 dehydrogenase/reductase (SDR family) member 2 protein_coding Danio_rerio
ENSMUSG00000022209 Dhrs2 dehydrogenase/reductase member 2 protein_coding Mus_musculus

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