C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutathione synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100983 GSS 9606 - 20:34928430-34955817 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216951 GSS-001 34928430-34955817 protein_coding
  ENST00000451957 GSS-201 34928828-34951852 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216951ENST00000451957
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216951 8.548±0.00 15.012±0.00 2.927±0.00 7.588±2.97 7.911±5.80 4.838±0.16 4.160±3.70 25.194±0.00 9.141±8.17 4.523±2.54 5.373±2.39 12.312±5.46 21.256±7.57 8.373±3.93
ENST00000451957 N/A N/A N/A N/A 2.493±0.00 N/A N/A N/A 0.874±0.00 N/A N/A 20.700±15.60 18.123±0.00 10.860±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005BF CIL_0005BF_0001 CGP 20:34872146-34955817
CIL_0005BE CIL_0005BE_0001 CGP 20:34928430-35002437

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004363 TAS:IEA glutathione synthase activity
GO:0005524 IDA:IEA ATP binding
GO:0005829 TAS cytosol
GO:0006520 TAS cellular amino acid metabolic process
GO:0006750 IEA glutathione biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0006979 TAS response to oxidative stress
GO:0007399 TAS nervous system development
GO:0007568 IEA aging
GO:0009410 IEA response to xenobiotic stimulus
GO:0016594 IEA glycine binding
GO:0031667 IEA response to nutrient levels
GO:0034612 IEA response to tumor necrosis factor
GO:0042277 IEA peptide binding
GO:0042803 IDA protein homodimerization activity
GO:0043200 IEA response to amino acid
GO:0043295 IDA glutathione binding
GO:0044281 TAS small molecule metabolic process
GO:0046686 IEA response to cadmium ion
GO:0070062 IDA extracellular vesicular exosome
GO:1901687 TAS glutathione derivative biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037706 gss glutathione synthetase protein_coding Danio_rerio
ENSMUSG00000027610 Gss glutathione synthetase protein_coding Mus_musculus

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