C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serum/glucocorticoid regulated kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101049 SGK2 9606 + 20:43558968-43588237 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341458 SGK2-002 43565763-43585677 protein_coding
  ENST00000373077 SGK2-010 43559027-43585300 nonsense_mediated_decay
  ENST00000373092 SGK2-001 43559042-43585677 protein_coding
  ENST00000373100 SGK2-005 43558968-43585677 protein_coding
  ENST00000412111 SGK2-007 43565228-43572137 protein_coding
  ENST00000423407 SGK2-201 43565115-43585632 protein_coding
  ENST00000426287 SGK2-011 43566316-43585016 protein_coding
  ENST00000485914 SGK2-003 43569469-43570996 processed_transcript
  ENST00000496343 SGK2-004 43559042-43588237 nonsense_mediated_decay
  ENST00000617268 SGK2-009 43564786-43566525 protein_coding
  ENST00000617358 SGK2-008 43565185-43569643 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaENST00000341458ENST00000373077ENST00000373092ENST00000423407ENST00000496343
Transcript ID Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta
ENST00000341458 N/A N/A N/A N/A N/A 0.384±0.00 N/A 1.754±0.00 N/A
ENST00000373077 N/A N/A N/A 0.199±0.00 N/A N/A N/A 5.553±0.00 N/A
ENST00000373092 N/A 12.424±0.00 N/A N/A N/A N/A N/A N/A 0.484±0.02
ENST00000423407 4.485±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000496343 2.972±0.00 5.592±0.00 0.651±0.00 N/A 8.980±7.32 15.265±0.00 0.256±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044M CIL_00044M_0001 CGP 20:43558968-43647296

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 TAS regulation of cell growth
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006468 IEA:NAS protein phosphorylation
GO:0006979 TAS response to oxidative stress
GO:0015459 IDA potassium channel regulator activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017080 NAS sodium channel regulator activity
GO:0032411 TAS positive regulation of transporter activity
GO:0034220 TAS ion transmembrane transport
GO:0035556 TAS intracellular signal transduction
GO:0042127 TAS regulation of cell proliferation
GO:0055085 TAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063370 sgk2a serum/glucocorticoid regulated kinase 2a protein_coding Danio_rerio
ENSMUSG00000017868 Sgk2 serum/glucocorticoid regulated kinase 2 protein_coding Mus_musculus

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