C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Src-like-adaptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101082 SLA2 9606 - 20:36612318-36646216 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262866 SLA2-001 36612318-36646216 protein_coding
  ENST00000360672 SLA2-002 36612519-36645881 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainKidneyLungOvaryPlacentaENST00000262866
Transcript ID Adrenal Brain Kidney Lung Ovary Placenta
ENST00000262866 6.187±0.00 2.786±0.00 2.930±2.53 3.112±1.77 6.823±0.00 3.558±0.62

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000304 CIL_000304_0002 CGP 20:36612318-36746078

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0005070 IDA SH3/SH2 adaptor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 TAS cytoplasm
GO:0005770 IEA late endosome
GO:0005886 TAS plasma membrane
GO:0009967 IDA positive regulation of signal transduction
GO:0010008 NAS endosome membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0019724 TAS B cell mediated immunity
GO:0030522 TAS intracellular receptor signaling pathway
GO:0042110 TAS T cell activation
GO:0047485 IPI protein N-terminus binding
GO:0050776 NAS regulation of immune response
GO:0050849 IDA negative regulation of calcium-mediated signaling
GO:0050851 TAS antigen receptor-mediated signaling pathway
GO:0050869 TAS negative regulation of B cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020788 sla2 Src-like-adaptor 2 protein_coding Danio_rerio
ENSMUSG00000027636 Sla2 Src-like-adaptor 2 protein_coding Mus_musculus

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