C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pre-mRNA processing factor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101161 PRPF6 9606 + 20:63981135-64033100 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000266079 PRPF6-001 63981135-64033100 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000266079
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000266079 40.495±0.00 32.710±0.00 2.614±0.00 22.054±12.67 26.213±14.17 19.653±13.09 10.312±6.04 19.588±12.31 11.268±1.31 15.682±8.54 25.842±20.16 57.394±31.81 37.585±7.53 56.924±8.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004F5 CIL_0004F5_0001 CGP 20:63939829-64048758

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000244 IC spliceosomal tri-snRNP complex assembly
GO:0000245 NAS spliceosomal complex assembly
GO:0000375 NAS RNA splicing, via transesterification reactions
GO:0000398 IC:IEA mRNA splicing, via spliceosome
GO:0003713 IGI transcription coactivator activity
GO:0003723 IDA RNA binding
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005681 NAS spliceosomal complex
GO:0005682 IDA U5 snRNP
GO:0006396 IEA RNA processing
GO:0006403 IMP RNA localization
GO:0008380 NAS RNA splicing
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0043021 IDA ribonucleoprotein complex binding
GO:0044822 IDA poly(A) RNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046540 IDA U4/U6 x U5 tri-snRNP complex
GO:0050681 IPI androgen receptor binding
GO:0071001 IDA U4/U6 snRNP
GO:0071013 IDA catalytic step 2 spliceosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014500 pre-mRNA processing factor 6 protein_coding Danio_rerio
ENSDARG00000091367 prpf6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000002455 Prpf6 PRP6 pre-mRNA splicing factor 6 homolog (yeast) protein_coding Mus_musculus

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