C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acyl-CoA thioesterase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101473 ACOT8 9606 - 20:45841721-45857406 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000217455 ACOT8-001 45841721-45857406 protein_coding
  ENST00000426915 ACOT8-003 45853422-45857309 protein_coding
  ENST00000457981 ACOT8-004 45853420-45857196 protein_coding
  ENST00000461272 ACOT8-002 45841726-45857389 nonsense_mediated_decay
  ENST00000481938 ACOT8-007 45848533-45857405 nonsense_mediated_decay
  ENST00000483141 ACOT8-011 45842747-45857369 nonsense_mediated_decay
  ENST00000484783 ACOT8-009 45843723-45857397 retained_intron
  ENST00000484975 ACOT8-012 45842023-45849110 retained_intron
  ENST00000486165 ACOT8-005 45844263-45857371 nonsense_mediated_decay
  ENST00000487205 ACOT8-008 45841765-45855284 protein_coding
  ENST00000488679 ACOT8-006 45841738-45857402 nonsense_mediated_decay
  ENST00000493118 ACOT8-010 45842023-45857371 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000217455ENST00000461272ENST00000484783ENST00000484975ENST00000486165ENST00000488679ENST00000493118
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000217455 N/A 6.856±0.00 N/A 9.406±4.20 15.388±0.00 8.295±3.06 7.285±0.00 7.758±6.35 6.848±0.00 6.804±0.00 18.865±0.00 9.416±6.43 15.405±2.50 16.339±1.39
ENST00000461272 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.128±0.00 N/A N/A
ENST00000484783 N/A N/A 1.951±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000484975 2.640±0.00 N/A N/A 1.395±0.00 N/A 2.023±0.00 1.184±0.75 2.527±0.00 0.663±0.00 2.255±0.00 N/A 4.804±2.53 N/A 1.626±0.00
ENST00000486165 N/A N/A N/A 7.262±0.00 N/A N/A 1.657±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000488679 N/A N/A N/A N/A N/A N/A N/A N/A 9.150±0.00 8.806±0.00 4.882±0.00 N/A N/A N/A
ENST00000493118 N/A 1.722±0.00 N/A 1.623±0.00 3.157±1.48 N/A N/A N/A 0.727±0.00 N/A 0.404±0.00 N/A 2.137±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000IO CIL_0000IO_0001 CGP 20:45823214-45843275
CIL_00002M CIL_00002M_0001 CGP 20:45833810-45857406
CIL_00002D CIL_00002D_0001 CGP 20:45841721-45879122

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005777 IEA peroxisome
GO:0005782 IDA peroxisomal matrix
GO:0006637 IDA:IEA acyl-CoA metabolic process
GO:0006699 TAS bile acid biosynthetic process
GO:0008206 TAS bile acid metabolic process
GO:0016032 IEA viral process
GO:0016290 IDA palmitoyl-CoA hydrolase activity
GO:0016559 IDA peroxisome fission
GO:0033540 TAS fatty acid beta-oxidation using acyl-CoA oxidase
GO:0033559 TAS unsaturated fatty acid metabolic process
GO:0033882 IEA choloyl-CoA hydrolase activity
GO:0036109 TAS alpha-linolenic acid metabolic process
GO:0043649 IDA dicarboxylic acid catabolic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0047617 IDA:IEA acyl-CoA hydrolase activity
GO:0052689 IEA carboxylic ester hydrolase activity
GO:0052815 IDA medium-chain acyl-CoA hydrolase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014138 acot8 acyl-CoA thioesterase 8 protein_coding Danio_rerio
ENSMUSG00000017307 Acot8 acyl-CoA thioesterase 8 protein_coding Mus_musculus

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