C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101557 USP14 9606 + 18:158383-214629 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261601 USP14-003 158608-214629 protein_coding
  ENST00000383589 USP14-004 158591-211997 protein_coding
  ENST00000400266 USP14-002 158536-211350 protein_coding
  ENST00000578786 USP14-008 196539-211268 retained_intron
  ENST00000578942 USP14-005 158561-212601 retained_intron
  ENST00000580410 USP14-006 158557-163431 protein_coding
  ENST00000581983 USP14-007 158858-163454 protein_coding
  ENST00000582707 USP14-001 158383-211391 protein_coding
  ENST00000583119 USP14-009 163393-198110 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261601ENST00000383589ENST00000400266ENST00000578786ENST00000582707
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261601 8.426±0.00 8.444±0.00 N/A 11.117±0.00 10.238±0.00 7.313±0.00 5.208±0.00 6.481±0.00 3.813±0.00 4.107±0.00 5.770±0.00 11.592±1.87 8.518±2.97 6.810±0.13
ENST00000383589 7.874±0.00 10.634±0.00 N/A N/A 11.297±0.00 7.204±0.00 7.770±0.00 11.804±0.00 6.260±0.00 5.011±0.00 4.160±1.63 N/A 6.832±0.05 9.541±0.00
ENST00000400266 N/A N/A N/A N/A N/A N/A 2.791±0.00 N/A N/A N/A 2.572±0.00 N/A N/A N/A
ENST00000578786 N/A N/A N/A N/A N/A N/A N/A 6.452±0.00 N/A N/A N/A N/A N/A N/A
ENST00000582707 N/A N/A 2.749±0.00 N/A N/A N/A N/A N/A 7.885±0.00 11.874±0.00 N/A 13.010±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 IEA proteasome complex
GO:0004197 TAS cysteine-type endopeptidase activity
GO:0004221 IDA ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0004866 IMP endopeptidase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007268 IEA synaptic transmission
GO:0008193 TAS tRNA guanylyltransferase activity
GO:0008234 IEA cysteine-type peptidase activity
GO:0009986 IDA cell surface
GO:0010951 IMP negative regulation of endopeptidase activity
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016579 IDA protein deubiquitination
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0045202 IEA synapse
GO:0050920 IMP regulation of chemotaxis
GO:0061136 IMP regulation of proteasomal protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0070628 IDA proteasome binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025889 usp14 ubiquitin specific protease 14 (tRNA-guanine transglycosylase) protein_coding Danio_rerio
ENSMUSG00000047879 Usp14 ubiquitin specific peptidase 14 protein_coding Mus_musculus

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