C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000582707 USP14-001 ENSG00000101557 9606 + 18:158383-211391 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderLiverLungOvaryENST00000582707
Transcript ID Bladder Liver Lung Ovary
ENST00000582707 2.749±0.00 7.885±0.00 11.874±0.00 13.010±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000502 IEA proteasome complex
GO:0004197 TAS cysteine-type endopeptidase activity
GO:0004221 IDA ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0004866 IMP endopeptidase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008193 TAS tRNA guanylyltransferase activity
GO:0009986 IDA cell surface
GO:0010951 IMP negative regulation of endopeptidase activity
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016579 IDA protein deubiquitination
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0050920 IMP regulation of chemotaxis
GO:0061136 IMP regulation of proteasomal protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0070628 IDA proteasome binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000116669 Usp14-002 protein_coding Mus_musculus 0 1964
ENSMUST00000092096 Usp14-001 protein_coding Mus_musculus 0 1648
ENSMUST00000154088 Usp14-006 retained_intron Mus_musculus 0 538
ENSMUST00000128334 Usp14-004 retained_intron Mus_musculus 0 448
ENSMUST00000145929 Usp14-007 retained_intron Mus_musculus 0 268
ENSMUST00000133594 Usp14-005 retained_intron Mus_musculus 0 268

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