C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glycine receptor, alpha 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101958 GLRA2 9606 + X:14529298-14731812 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000218075 GLRA2-001 14529528-14731812 protein_coding
  ENST00000355020 GLRA2-003 14529772-14730570 protein_coding
  ENST00000415367 GLRA2-002 14531146-14607247 protein_coding
  ENST00000443437 GLRA2-201 14529298-14731809 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonLiverLungOvaryPlacentaENST00000218075ENST00000355020ENST00000415367ENST00000443437
Transcript ID Brain Colon Liver Lung Ovary Placenta
ENST00000218075 0.646±0.23 0.022±0.00 0.002±0.00 N/A N/A N/A
ENST00000355020 0.771±0.00 0.182±0.07 N/A N/A N/A 0.026±0.00
ENST00000415367 N/A N/A N/A N/A N/A 0.088±0.02
ENST00000443437 0.155±0.00 N/A 0.016±0.00 0.014±0.00 0.050±0.03 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002U1 CIL_0002U1_0002 CGP X:14529298-14873069

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006810 IEA transport
GO:0006811 IDA:IEA ion transport
GO:0007218 IDA neuropeptide signaling pathway
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016594 IDA glycine binding
GO:0016934 IDA extracellular-glycine-gated chloride channel activity
GO:0022824 IEA transmitter-gated ion channel activity
GO:0030054 IEA cell junction
GO:0034220 TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0045211 IEA postsynaptic membrane
GO:0055085 TAS transmembrane transport
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075012 glra2 glycine receptor, alpha 2 protein_coding Danio_rerio
ENSMUSG00000018589 Glra2 glycine receptor, alpha 2 subunit protein_coding Mus_musculus

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