C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Pim-2 proto-oncogene, serine/threonine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102096 PIM2 9606 - X:48913182-48919024 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376509 PIM2-001 48913182-48919024 protein_coding
  ENST00000442430 PIM2-002 48914396-48915735 protein_coding
  ENST00000485431 PIM2-003 48914104-48914914 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376509ENST00000442430ENST00000485431
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376509 2.767±0.00 34.838±0.00 0.223±0.00 2.611±2.33 1.761±0.91 4.259±0.00 0.668±0.65 3.826±0.00 0.962±0.66 14.407±12.58 1.161±1.12 7.205±2.41 3.065±1.20 4.261±1.03
ENST00000442430 N/A N/A N/A N/A 1.860±0.00 1.288±0.00 N/A N/A N/A N/A 0.090±0.00 N/A N/A N/A
ENST00000485431 N/A N/A 0.234±0.00 N/A N/A 2.045±0.00 0.577±0.00 N/A N/A 1.978±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IDA G1/S transition of mitotic cell cycle
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA:ISS protein phosphorylation
GO:0007140 TAS male meiosis
GO:0008283 TAS cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0008637 IEA apoptotic mitochondrial changes
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0009615 IEP response to virus
GO:0010508 ISS positive regulation of autophagy
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0043066 IDA negative regulation of apoptotic process
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0050821 ISS protein stabilization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000031155 Pim2 proviral integration site 2 protein_coding Mus_musculus

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