C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Pim-2 proto-oncogene, serine/threonine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000376509 PIM2-001 ENSG00000102096 9606 - X:48913182-48919024 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376509
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376509 2.767±0.00 34.838±0.00 0.223±0.00 2.611±2.33 1.761±0.91 4.259±0.00 0.668±0.65 3.826±0.00 0.962±0.66 14.407±12.58 1.161±1.12 7.205±2.41 3.065±1.20 4.261±1.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IDA G1/S transition of mitotic cell cycle
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA:ISS protein phosphorylation
GO:0007140 TAS male meiosis
GO:0008283 TAS cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0008637 IEA apoptotic mitochondrial changes
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0009615 IEP response to virus
GO:0010508 ISS positive regulation of autophagy
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0043066 IDA negative regulation of apoptotic process
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0050821 ISS protein stabilization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000190448 Pim2-201 protein_coding Mus_musculus 0 1696
ENSMUST00000033495 Pim2-001 protein_coding Mus_musculus 0 1696
ENSMUST00000119008 Gm7645-001 processed_pseudogene Mus_musculus 0 721
ENSMUST00000178899 Gm21182-201 processed_pseudogene Mus_musculus 0 625
ENSMUST00000126715 Pim2-002 retained_intron Mus_musculus 0 501
ENSMUST00000042818 Pim3-201 protein_coding Mus_musculus 4e-30 137

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