C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102225 CDK16 9606 + X:47217860-47229997 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000276052 CDK16-201 47223018-47229993 protein_coding
  ENST00000357227 CDK16-001 47218688-47229997 protein_coding
  ENST00000428400 CDK16-006 47222853-47228990 retained_intron
  ENST00000457458 CDK16-002 47218233-47229997 protein_coding
  ENST00000462483 CDK16-004 47228204-47228816 retained_intron
  ENST00000462827 CDK16-019 47227181-47229471 protein_coding
  ENST00000493213 CDK16-003 47227123-47228143 retained_intron
  ENST00000517426 CDK16-010 47218718-47229415 protein_coding
  ENST00000517479 CDK16-014 47218027-47222330 processed_transcript
  ENST00000517997 CDK16-013 47217860-47222380 processed_transcript
  ENST00000518022 CDK16-007 47223009-47228990 protein_coding
  ENST00000518391 CDK16-005 47222132-47225036 protein_coding
  ENST00000519758 CDK16-022 47218691-47224731 protein_coding
  ENST00000520141 CDK16-017 47227181-47228991 protein_coding
  ENST00000520295 CDK16-020 47218387-47224473 nonsense_mediated_decay
  ENST00000520893 CDK16-023 47218710-47224740 protein_coding
  ENST00000522234 CDK16-008 47218776-47226578 retained_intron
  ENST00000522883 CDK16-021 47218311-47223728 protein_coding
  ENST00000523034 CDK16-015 47223638-47225044 protein_coding
  ENST00000523344 CDK16-012 47225965-47229251 protein_coding
  ENST00000523543 CDK16-018 47226492-47227452 retained_intron
  ENST00000523699 CDK16-016 47226096-47227223 retained_intron
  ENST00000622098 CDK16-202 47218716-47229993 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357227ENST00000457458ENST00000517426ENST00000518022ENST00000520141ENST00000520893ENST00000522234ENST00000523344ENST00000523543ENST00000523699ENST00000622098
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357227 N/A 7.508±0.00 N/A N/A N/A N/A 1.688±0.00 8.299±0.00 0.616±0.00 12.919±0.00 5.150±0.00 9.148±5.14 15.178±2.99 N/A
ENST00000457458 N/A N/A N/A 3.068±0.00 N/A N/A N/A N/A N/A N/A N/A 5.133±2.15 N/A 9.789±2.30
ENST00000517426 16.878±0.00 N/A N/A 23.715±0.00 21.014±0.00 9.099±0.00 17.500±16.08 9.895±8.38 2.626±0.00 22.721±0.00 88.741±0.00 19.600±0.00 18.721±8.09 15.437±3.43
ENST00000518022 N/A N/A 3.317±0.00 3.303±0.00 1.341±0.00 N/A 0.791±0.00 N/A N/A N/A 17.778±0.00 11.431±9.37 9.038±0.00 11.339±2.64
ENST00000520141 39.048±0.00 32.541±0.00 N/A N/A 36.144±0.00 N/A N/A N/A N/A N/A 109.258±0.00 N/A N/A 29.559±0.00
ENST00000520893 N/A N/A N/A N/A N/A N/A 1.821±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000522234 N/A N/A N/A N/A 2.865±0.00 N/A N/A N/A N/A N/A N/A 12.593±0.00 N/A N/A
ENST00000523344 24.103±0.00 16.779±0.00 8.382±0.00 18.682±9.10 29.011±0.00 10.374±5.39 8.553±7.12 13.113±12.21 4.569±2.11 13.564±10.57 N/A 15.468±0.50 14.352±0.82 18.888±0.00
ENST00000523543 N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.033±0.00 21.999±0.00 7.322±0.00 N/A N/A
ENST00000523699 N/A N/A N/A N/A N/A N/A N/A 1.565±0.00 N/A N/A N/A N/A N/A N/A
ENST00000622098 8.380±0.00 N/A N/A 13.334±0.00 8.106±0.00 6.252±0.00 11.174±0.00 5.765±0.00 4.092±0.00 N/A N/A 7.536±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G8 CIL_0005G8_0001 CGP X:47190861-47229997
CIL_0005GD CIL_0005GD_0001 CGP X:47217860-47248328

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006887 ISS exocytosis
GO:0007283 ISS spermatogenesis
GO:0008021 ISS synaptic vesicle
GO:0015630 IDA microtubule cytoskeleton
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030054 IEA cell junction
GO:0030252 ISS growth hormone secretion
GO:0031175 ISS neuron projection development
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0043005 IEA neuron projection
GO:0051726 IEA regulation of cell cycle
GO:0061178 IMP regulation of insulin secretion involved in cellular response to glucose stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032072 cdk16 cyclin-dependent kinase 16 protein_coding Danio_rerio
ENSMUSG00000031065 Cdk16 cyclin-dependent kinase 16 protein_coding Mus_musculus

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