C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Kruppel-like factor 5 (intestinal)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102554 KLF5 9606 + 13:73054976-73077542 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377687 KLF5-001 73058792-73077542 protein_coding
  ENST00000464404 KLF5-004 73075015-73075778 processed_transcript
  ENST00000476859 KLF5-003 73060579-73062542 processed_transcript
  ENST00000477333 KLF5-002 73054976-73062661 processed_transcript
  ENST00000539231 KLF5-201 73054976-73077541 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377687ENST00000476859ENST00000477333ENST00000539231
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377687 2.670±0.00 0.548±0.00 0.341±0.00 0.289±0.00 5.793±0.63 20.035±14.21 0.726±0.00 4.946±0.00 0.236±0.00 8.645±5.99 4.408±4.08 16.401±8.08 7.405±2.40 4.416±2.67
ENST00000476859 N/A N/A N/A N/A N/A N/A N/A 0.186±0.00 N/A N/A 3.471±0.00 N/A N/A 9.184±0.00
ENST00000477333 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.064±0.00
ENST00000539231 N/A N/A 0.205±0.00 N/A N/A 8.579±0.00 N/A 0.152±0.00 4.868±0.00 4.129±0.00 N/A 7.707±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00015J CIL_00015J_0001 CGP 13:72782059-73077542
CIL_00051S CIL_00051S_0001 CGP 13:73054976-74133905

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IEA angiogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0008284 IEA positive regulation of cell proliferation
GO:0030033 IEA microvillus assembly
GO:0032534 IEA regulation of microvillus assembly
GO:0035914 IEA skeletal muscle cell differentiation
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045600 IEA positive regulation of fat cell differentiation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0060576 IEA intestinal epithelial cell development
GO:0071407 IEA cellular response to organic cyclic compound
GO:1901653 IEA cellular response to peptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015506 klf5a Kruppel-like factor 5a protein_coding Danio_rerio
ENSDARG00000062106 klf5b Kruppel-like factor 5b protein_coding Danio_rerio
ENSMUSG00000005148 Klf5 Kruppel-like factor 5 protein_coding Mus_musculus

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