C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Kruppel-like factor 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005148 Klf5 10090 + 14:99298691-99313405 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005279 Klf5-201 99298691-99313405 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005279
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005279 3.791±3.48 5.519±0.29 26.942±1.53 1.416±0.45 5.517±0.31 246.509±16.61 0.757±0.43 2.693±0.28 0.288±0.25 28.409±3.07 0.616±0.25 9.353±3.20 2.752±2.03 2.231±0.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00015J CIL_00015J_0002 CGP 14:99099433-99313405
CIL_00051S CIL_00051S_0002 CGP 14:99298691-100149764

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IMP angiogenesis
GO:0003677 IDA DNA binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0008284 IEA positive regulation of cell proliferation
GO:0030033 IMP microvillus assembly
GO:0032534 IMP regulation of microvillus assembly
GO:0035914 IMP skeletal muscle cell differentiation
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045600 IMP positive regulation of fat cell differentiation
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0060576 IMP intestinal epithelial cell development
GO:0071407 IEA cellular response to organic cyclic compound
GO:1901653 IEA cellular response to peptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015506 klf5a Kruppel-like factor 5a protein_coding Danio_rerio
ENSDARG00000062106 klf5b Kruppel-like factor 5b protein_coding Danio_rerio
ENSG00000102554 KLF5 Kruppel-like factor 5 (intestinal) protein_coding Homo_sapiens

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