C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulator of cell cycle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102760 RGCC 9606 + 13:41457559-41470882 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000379359 RGCC-001 41457559-41470882 protein_coding
  ENST00000487837 RGCC-002 41464115-41468844 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379359ENST00000487837
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379359 83.350±0.00 7.712±0.00 1.565±0.00 17.551±6.96 16.530±14.80 24.331±20.35 24.155±18.07 20.726±0.00 3.472±2.91 201.360±161.70 6.664±0.60 9.308±3.94 108.597±43.14 11.910±4.05
ENST00000487837 N/A N/A N/A N/A N/A N/A N/A N/A 0.369±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005Y6 CIL_0005Y6_0002 CGP 13:41457559-41961120

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001100 IDA negative regulation of exit from mitosis
GO:0001937 IDA negative regulation of endothelial cell proliferation
GO:0003331 IDA positive regulation of extracellular matrix constituent secretion
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0006956 IMP complement activation
GO:0008285 IMP negative regulation of cell proliferation
GO:0010628 IDA positive regulation of gene expression
GO:0010718 IMP positive regulation of epithelial to mesenchymal transition
GO:0016525 IDA negative regulation of angiogenesis
GO:0019901 ISS protein kinase binding
GO:0030295 IDA protein kinase activator activity
GO:0031659 IDA positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
GO:0032967 IDA positive regulation of collagen biosynthetic process
GO:0043537 IDA negative regulation of blood vessel endothelial cell migration
GO:0045840 IMP positive regulation of mitosis
GO:0050710 IMP negative regulation of cytokine secretion
GO:0050715 IMP positive regulation of cytokine secretion
GO:0051091 IMP positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051496 IDA positive regulation of stress fiber assembly
GO:0070412 IPI R-SMAD binding
GO:0071158 IDA positive regulation of cell cycle arrest
GO:0071456 IMP cellular response to hypoxia
GO:0071850 IDA mitotic cell cycle arrest
GO:0072537 ISS fibroblast activation
GO:0090272 IDA negative regulation of fibroblast growth factor production
GO:1901313 IDA positive regulation of gene expression involved in extracellular matrix organization
GO:1901991 IDA negative regulation of mitotic cell cycle phase transition
GO:2000048 IDA negative regulation of cell-cell adhesion mediated by cadherin
GO:2000353 IDA positive regulation of endothelial cell apoptotic process
GO:2000573 ISS positive regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035810 rgcc regulator of cell cycle protein_coding Danio_rerio
ENSMUSG00000022018 Rgcc regulator of cell cycle protein_coding Mus_musculus

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