C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock transcription factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102878 HSF4 9606 + 16:67163385-67169945 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264009 HSF4-201 67163385-67169945 protein_coding
  ENST00000434833 HSF4-008 67164744-67169910 nonsense_mediated_decay
  ENST00000517680 HSF4-016 67166185-67167479 retained_intron
  ENST00000517685 HSF4-012 67164812-67169783 protein_coding
  ENST00000517729 HSF4-026 67165525-67167490 protein_coding
  ENST00000517750 HSF4-027 67166047-67169040 protein_coding
  ENST00000517867 HSF4-025 67166333-67167381 processed_transcript
  ENST00000519105 HSF4-022 67166311-67167222 retained_intron
  ENST00000519224 HSF4-015 67165839-67167917 nonsense_mediated_decay
  ENST00000519601 HSF4-018 67167171-67169781 protein_coding
  ENST00000520247 HSF4-023 67167421-67167804 retained_intron
  ENST00000520304 HSF4-028 67167839-67169941 protein_coding
  ENST00000520528 HSF4-020 67167380-67169903 nonsense_mediated_decay
  ENST00000520833 HSF4-019 67167188-67169710 retained_intron
  ENST00000521314 HSF4-009 67164771-67169929 nonsense_mediated_decay
  ENST00000521374 HSF4-006 67164812-67169821 protein_coding
  ENST00000521624 HSF4-011 67164790-67169941 nonsense_mediated_decay
  ENST00000521916 HSF4-024 67169074-67169941 protein_coding
  ENST00000522023 HSF4-013 67164745-67166154 retained_intron
  ENST00000522027 HSF4-021 67166257-67167543 retained_intron
  ENST00000522295 HSF4-007 67164743-67169939 nonsense_mediated_decay
  ENST00000522459 HSF4-017 67166276-67167292 retained_intron
  ENST00000522870 HSF4-005 67164681-67168883 retained_intron
  ENST00000523077 HSF4-014 67164900-67165815 retained_intron
  ENST00000523562 HSF4-010 67164790-67169945 nonsense_mediated_decay
  ENST00000584272 HSF4-001 67164812-67169945 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLungMuscleOvaryTestisENST00000434833ENST00000517680ENST00000517729ENST00000520528ENST00000520833ENST00000521314ENST00000521374ENST00000521624ENST00000521916ENST00000522023ENST00000522870ENST00000523077ENST00000523562
Transcript ID Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Testis
ENST00000434833 N/A N/A N/A N/A N/A N/A N/A 0.764±0.00 N/A N/A
ENST00000517680 2.102±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000517729 1.612±0.00 N/A 4.854±0.00 N/A 0.476±0.00 N/A N/A N/A 2.078±0.00 N/A
ENST00000520528 N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.401±0.00
ENST00000520833 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.877±0.00
ENST00000521314 N/A 6.279±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000521374 N/A N/A N/A 0.374±0.00 N/A N/A 1.055±0.00 N/A N/A N/A
ENST00000521624 N/A N/A N/A 0.498±0.00 N/A N/A N/A N/A N/A N/A
ENST00000521916 N/A N/A N/A N/A N/A N/A N/A 3.964±0.00 N/A N/A
ENST00000522023 N/A N/A N/A N/A 0.402±0.00 1.608±0.00 N/A N/A N/A N/A
ENST00000522870 0.883±0.00 0.978±0.00 2.483±0.00 N/A N/A N/A 1.313±0.00 N/A 10.219±9.35 N/A
ENST00000523077 0.935±0.00 N/A 1.981±0.00 1.353±0.00 N/A 1.363±0.00 N/A N/A 2.244±0.00 N/A
ENST00000523562 N/A 1.273±0.00 N/A N/A N/A N/A N/A 2.062±1.49 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WN CIL_0007WN_0001 VISTA 16:66603173-67205657
CIL_0005T4 CIL_0005T4_0001 CGP 16:67154180-67164570
CIL_0005T7 CIL_0005T7_0001 CGP 16:67159931-67169945

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001654 IEA eye development
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005634 IDA:IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS:IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006950 IEA response to stress
GO:0008284 IEA positive regulation of cell proliferation
GO:0019903 IPI protein phosphatase binding
GO:0033169 IEA histone H3-K9 demethylation
GO:0043010 IEA camera-type eye development
GO:0043565 IEA sequence-specific DNA binding
GO:0045597 IEA positive regulation of cell differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048468 IEA cell development
GO:0070207 IEA protein homotrimerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013251 hsf4 heat shock transcription factor 4 protein_coding Danio_rerio
ENSMUSG00000033249 Hsf4 heat shock transcription factor 4 protein_coding Mus_musculus

Loading