C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock transcription factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033249 Hsf4 10090 + 8:105269801-105275845 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036127 Hsf4-001 105269801-105275845 protein_coding
  ENSMUST00000163734 Hsf4-201 105269801-105275845 protein_coding
  ENSMUST00000172525 Hsf4-005 105269856-105275736 protein_coding
  ENSMUST00000173102 Hsf4-002 105269829-105275843 nonsense_mediated_decay
  ENSMUST00000173640 Hsf4-004 105269801-105275686 nonsense_mediated_decay
  ENSMUST00000173859 Hsf4-003 105269874-105275845 protein_coding
  ENSMUST00000174837 Hsf4-006 105269874-105275658 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036127ENSMUST00000163734ENSMUST00000172525ENSMUST00000173102ENSMUST00000173640ENSMUST00000173859ENSMUST00000174837
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036127 1.405±0.43 0.595±0.12 1.650±0.03 0.137±0.02 1.326±0.44 0.822±0.22 1.169±0.14 0.584±0.18 2.604±1.65 6.366±0.25 2.573±1.23 0.537±0.23 1.068±0.73 0.084±0.00
ENSMUST00000163734 N/A 0.172±0.04 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.234±0.00 N/A
ENSMUST00000172525 N/A N/A N/A N/A N/A N/A N/A N/A 0.006±0.00 N/A N/A N/A N/A 0.078±0.01
ENSMUST00000173102 0.564±0.00 N/A N/A 6.091±0.00 0.346±0.00 0.320±0.00 0.496±0.21 0.226±0.00 0.021±0.00 N/A 1.210±0.51 N/A 0.407±0.16 0.038±0.00
ENSMUST00000173640 1.195±0.33 0.477±0.23 0.828±0.13 0.074±0.03 1.336±0.29 0.403±0.34 0.885±0.21 0.201±0.06 0.862±0.66 4.751±1.31 1.567±0.20 0.523±0.28 0.594±0.11 0.019±0.00
ENSMUST00000173859 N/A N/A N/A 2.955±0.00 0.488±0.07 N/A 0.291±0.00 N/A 0.023±0.01 N/A N/A 0.246±0.00 0.359±0.00 0.075±0.00
ENSMUST00000174837 0.665±0.10 N/A N/A 13.010±0.00 N/A N/A 0.456±0.00 N/A 0.006±0.00 N/A N/A 0.543±0.36 0.457±0.36 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005T7 CIL_0005T7_0002 CGP 8:105264648-105275845

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001654 IMP eye development
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006950 IEA response to stress
GO:0008284 IGI positive regulation of cell proliferation
GO:0019903 IEA protein phosphatase binding
GO:0033169 IDA histone H3-K9 demethylation
GO:0043010 IMP camera-type eye development
GO:0043565 IDA sequence-specific DNA binding
GO:0045597 IMP positive regulation of cell differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048468 IMP cell development
GO:0070207 IDA protein homotrimerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013251 hsf4 heat shock transcription factor 4 protein_coding Danio_rerio
ENSG00000102878 HSF4 heat shock transcription factor 4 protein_coding Homo_sapiens

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