C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: matrix metallopeptidase 15 (membrane-inserted)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102996 MMP15 9606 + 16:58025566-58046901 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219271 MMP15-001 58025566-58046901 protein_coding
  ENST00000570065 MMP15-002 58040165-58040867 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000219271
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000219271 2.862±0.00 3.340±0.00 0.869±0.00 2.541±1.38 11.786±8.36 6.724±1.50 9.934±6.04 6.827±3.49 12.729±12.02 4.265±2.90 1.433±0.64 6.214±4.29 67.059±20.88 19.009±1.81

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Z0 CIL_0008Z0_0001 VISTA 16:57818949-58421282
CIL_0004RY CIL_0004RY_0001 CGP 16:57999546-58046901
CIL_0004RX CIL_0004RX_0001 CGP 16:58025566-58129450

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006464 TAS cellular protein modification process
GO:0006508 IEA proteolysis
GO:0008047 TAS enzyme activator activity
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030574 TAS collagen catabolic process
GO:0031012 IEA extracellular matrix
GO:0032355 IEA response to estradiol
GO:0035987 IEP endodermal cell differentiation
GO:0043085 TAS positive regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013072 MMP15 (1 of 2) matrix metallopeptidase 15 (membrane-inserted) protein_coding Danio_rerio
ENSDARG00000051962 mmp15a matrix metallopeptidase 15a protein_coding Danio_rerio
ENSMUSG00000031790 Mmp15 matrix metallopeptidase 15 protein_coding Mus_musculus

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