C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: N-methylpurine-DNA glycosylase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103152 MPG 9606 + 16:77007-85853 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219431 MPG-001 78257-85842 protein_coding
  ENST00000356432 MPG-002 78063-85853 protein_coding
  ENST00000397817 MPG-201 77019-85851 protein_coding
  ENST00000436333 MPG-004 77007-85684 protein_coding
  ENST00000475280 MPG-003 78244-79844 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356432ENST00000436333
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356432 N/A N/A 0.937±0.00 3.823±0.00 1.196±0.00 7.857±0.00 5.061±4.05 2.207±0.00 4.250±2.16 N/A N/A 19.632±0.00 16.833±1.28 N/A
ENST00000436333 20.575±0.00 27.287±0.00 N/A 12.771±0.00 18.746±0.00 8.061±6.80 N/A N/A 7.064±0.00 0.862±0.00 3.863±0.00 6.498±4.29 15.217±4.37 15.744±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00094P CIL_00094P_0001 VISTA 16:-195470-405616
CIL_0008HK CIL_0008HK_0001 VISTA 16:-187027-414801
CIL_0007A5 CIL_0007A5_0002 CGP 16:58059-85853
CIL_00031O CIL_00031O_0002 CGP 16:77007-138860

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003684 TAS damaged DNA binding
GO:0003824 IEA catalytic activity
GO:0003905 IBA:IEA alkylbase DNA N-glycosylase activity
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0006281 TAS DNA repair
GO:0006284 IBA:IEA base-excision repair
GO:0006285 TAS base-excision repair, AP site formation
GO:0006307 TAS DNA dealkylation involved in DNA repair
GO:0008725 IEA DNA-3-methyladenine glycosylase activity
GO:0042645 IEA mitochondrial nucleoid
GO:0043916 IEA DNA-7-methylguanine glycosylase activity
GO:0045007 TAS depurination
GO:0052821 IEA DNA-7-methyladenine glycosylase activity
GO:0052822 IEA DNA-3-methylguanine glycosylase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069729 mpg N-methylpurine-DNA glycosylase protein_coding Danio_rerio
ENSMUSG00000020287 Mpg N-methylpurine-DNA glycosylase protein_coding Mus_musculus

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