C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic elongation factor-2 kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103319 EEF2K 9606 + 16:22206282-22288732 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263026 EEF2K-001 22206282-22288732 protein_coding
  ENST00000561791 EEF2K-005 22286558-22287233 processed_transcript
  ENST00000563555 EEF2K-004 22257644-22263322 retained_intron
  ENST00000568269 EEF2K-002 22206326-22265245 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263026ENST00000568269
Transcript ID Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263026 0.948±0.00 1.267±0.86 3.709±0.00 N/A 1.225±0.00 1.883±0.00 1.579±0.00 3.180±2.44 3.255±1.62 1.504±0.10
ENST00000568269 N/A N/A N/A 0.874±0.00 4.095±0.00 1.009±0.00 1.802±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005T8 CIL_0005T8_0001 CGP 16:22206282-22335103

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 TAS protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004686 IDA:IEA elongation factor-2 kinase activity
GO:0005509 IEA calcium ion binding
GO:0005516 IDA:IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006414 TAS translational elongation
GO:0006468 IEA protein phosphorylation
GO:0008135 TAS translation factor activity, nucleic acid binding
GO:0008286 TAS insulin receptor signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031952 IEA regulation of protein autophosphorylation
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035835 eef2k elongation factor-2 kinase protein_coding Danio_rerio
ENSMUSG00000035064 Eef2k eukaryotic elongation factor-2 kinase protein_coding Mus_musculus

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