C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic elongation factor-2 kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035064 Eef2k 10090 + 7:120842831-120907219 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047875 Eef2k-001 120842831-120907219 protein_coding
  ENSMUST00000106487 Eef2k-004 120851189-120900372 protein_coding
  ENSMUST00000106488 Eef2k-003 120851201-120903496 protein_coding
  ENSMUST00000106489 Eef2k-002 120843600-120903994 protein_coding
  ENSMUST00000125828 Eef2k-007 120876223-120879861 retained_intron
  ENSMUST00000128813 Eef2k-009 120891855-120903578 processed_transcript
  ENSMUST00000143279 Eef2k-005 120843618-120858534 protein_coding
  ENSMUST00000143322 Eef2k-006 120851189-120880342 protein_coding
  ENSMUST00000146482 Eef2k-008 120889686-120895320 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047875ENSMUST00000106487ENSMUST00000106488ENSMUST00000106489ENSMUST00000128813
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047875 2.821±0.75 4.883±1.17 12.628±0.84 3.371±1.63 2.966±0.33 7.064±1.11 1.738±0.36 0.528±0.09 3.444±2.83 2.524±0.37 7.007±1.55 4.742±1.61 2.284±0.18 0.422±0.00
ENSMUST00000106487 N/A N/A N/A N/A N/A N/A 1.580±0.00 0.711±0.21 N/A N/A N/A N/A N/A N/A
ENSMUST00000106488 N/A N/A N/A N/A N/A N/A N/A 0.427±0.00 N/A N/A N/A 18.703±0.00 21.486±14.59 1.763±0.00
ENSMUST00000106489 4.696±0.38 N/A 24.612±0.74 6.266±0.24 5.610±1.79 4.708±0.00 5.535±0.39 0.947±0.26 8.010±6.35 1.695±0.14 13.567±2.36 9.270±5.22 13.921±7.61 1.961±0.55
ENSMUST00000128813 N/A N/A N/A 23.313±0.00 N/A N/A N/A N/A N/A N/A N/A 35.390±12.08 91.352±26.04 7.516±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005T8 CIL_0005T8_0002 CGP 7:120842831-120947432

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004686 IDA elongation factor-2 kinase activity
GO:0005509 IEA calcium ion binding
GO:0005516 IDA calmodulin binding
GO:0005524 IEA ATP binding
GO:0006414 TAS translational elongation
GO:0006468 IEA protein phosphorylation
GO:0008135 TAS translation factor activity, nucleic acid binding
GO:0031952 IDA regulation of protein autophosphorylation
GO:0046777 IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035835 eef2k elongation factor-2 kinase protein_coding Danio_rerio
ENSG00000103319 EEF2K eukaryotic elongation factor-2 kinase protein_coding Homo_sapiens

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