C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: K(lysine) acetyltransferase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103510 KAT8 9606 + 16:31115754-31131393 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219797 KAT8-201 31117664-31131389 protein_coding
  ENST00000448516 KAT8-002 31117664-31131359 protein_coding
  ENST00000537402 KAT8-004 31127272-31131393 protein_coding
  ENST00000538768 KAT8-003 31125584-31131393 retained_intron
  ENST00000539683 KAT8-006 31117697-31121118 retained_intron
  ENST00000543774 KAT8-001 31115754-31131393 protein_coding
  ENST00000573144 KAT8-007 31130456-31131359 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000219797ENST00000448516ENST00000538768ENST00000539683ENST00000543774
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000219797 12.418±0.00 15.247±0.00 1.299±0.00 7.225±4.89 5.541±4.20 10.074±9.08 7.085±5.55 8.669±5.20 8.039±0.00 11.088±8.44 14.653±7.84 21.007±16.61 18.174±3.78 19.505±8.80
ENST00000448516 N/A 4.001±0.00 N/A 3.638±1.08 3.653±0.00 0.984±0.00 N/A N/A 2.998±0.00 3.950±0.00 N/A N/A N/A 5.962±0.00
ENST00000538768 N/A 2.512±0.00 0.549±0.00 N/A N/A 0.530±0.00 0.250±0.00 N/A 0.789±0.00 0.421±0.00 N/A N/A N/A N/A
ENST00000539683 10.334±0.00 15.335±0.00 N/A 4.604±1.93 6.226±2.68 5.358±0.00 7.706±5.58 12.480±0.00 3.998±0.34 6.207±1.47 5.257±0.00 11.423±5.21 6.901±1.78 10.931±4.09
ENST00000543774 N/A N/A N/A 1.290±0.00 1.518±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00043A CIL_00043A_0001 CGP 16:31106107-31131393
CIL_00035R CIL_00035R_0001 CGP 16:31115754-31135762

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000123 IDA histone acetyltransferase complex
GO:0000776 IEA kinetochore
GO:0004402 IDA histone acetyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006325 TAS chromatin organization
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008134 IDA transcription factor binding
GO:0016407 IDA acetyltransferase activity
GO:0016573 IDA histone acetylation
GO:0016747 IEA transferase activity, transferring acyl groups other than amino-acyl groups
GO:0019899 IEA enzyme binding
GO:0030099 IDA myeloid cell differentiation
GO:0031965 IDA nuclear membrane
GO:0035064 IDA methylated histone binding
GO:0043981 IDA histone H4-K5 acetylation
GO:0043982 IDA histone H4-K8 acetylation
GO:0043984 IMP histone H4-K16 acetylation
GO:0043995 IDA histone acetyltransferase activity (H4-K5 specific)
GO:0043996 IDA histone acetyltransferase activity (H4-K8 specific)
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0046972 IDA histone acetyltransferase activity (H4-K16 specific)
GO:0071339 IDA MLL1 complex
GO:0072487 IDA MSL complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027187 kat8 K(lysine) acetyltransferase 8 protein_coding Danio_rerio
ENSMUSG00000030801 Kat8 K(lysine) acetyltransferase 8 protein_coding Mus_musculus

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