C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: K(lysine) acetyltransferase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030801 Kat8 10090 + 7:127912517-127925832 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033070 Kat8-201 127912517-127925832 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartLiverMuscleOvaryPlacentaTestisENSMUST00000033070
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Liver Muscle Ovary Placenta Testis
ENSMUST00000033070 6.839±2.03 8.354±1.37 8.599±1.31 12.703±2.17 9.220±1.93 3.765±0.48 7.414±1.54 8.014±1.30 11.878±2.14 12.456±0.64 51.852±8.54

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00043A CIL_00043A_0002 CGP 7:127904082-127925832
CIL_00035R CIL_00035R_0002 CGP 7:127912517-127930113

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000123 ISS histone acetyltransferase complex
GO:0000776 IDA kinetochore
GO:0004402 IEA histone acetyltransferase activity
GO:0005515 IEA protein binding
GO:0006351 IEA transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0016407 IDA acetyltransferase activity
GO:0016573 IEA histone acetylation
GO:0019899 IPI enzyme binding
GO:0030099 IEA myeloid cell differentiation
GO:0031965 IEA nuclear membrane
GO:0035064 IEA methylated histone binding
GO:0043981 ISS histone H4-K5 acetylation
GO:0043982 ISS histone H4-K8 acetylation
GO:0043984 ISS histone H4-K16 acetylation
GO:0043995 ISS histone acetyltransferase activity (H4-K5 specific)
GO:0043996 ISS histone acetyltransferase activity (H4-K8 specific)
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0046972 ISS histone acetyltransferase activity (H4-K16 specific)
GO:0071339 ISS MLL1 complex
GO:0072487 ISS MSL complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027187 kat8 K(lysine) acetyltransferase 8 protein_coding Danio_rerio
ENSG00000103510 KAT8 K(lysine) acetyltransferase 8 protein_coding Homo_sapiens

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