C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cathepsin H
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103811 CTSH 9606 - 15:78921058-78949574 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000220166 CTSH-001 78921058-78945091 protein_coding
  ENST00000525807 CTSH-002 78921769-78945062 nonsense_mediated_decay
  ENST00000527138 CTSH-018 78927207-78931953 retained_intron
  ENST00000527715 CTSH-005 78921765-78926904 retained_intron
  ENST00000528191 CTSH-015 78931885-78937186 processed_transcript
  ENST00000528436 CTSH-010 78937413-78945042 processed_transcript
  ENST00000528741 CTSH-007 78929412-78949574 protein_coding
  ENST00000529263 CTSH-019 78929441-78937715 retained_intron
  ENST00000529612 CTSH-016 78927609-78935750 retained_intron
  ENST00000529861 CTSH-008 78929411-78945094 nonsense_mediated_decay
  ENST00000530010 CTSH-012 78934844-78944998 retained_intron
  ENST00000530929 CTSH-006 78934847-78949501 retained_intron
  ENST00000533777 CTSH-003 78921775-78945046 nonsense_mediated_decay
  ENST00000534038 CTSH-009 78932006-78945046 processed_transcript
  ENST00000534237 CTSH-017 78922117-78932030 processed_transcript
  ENST00000534268 CTSH-011 78937318-78945021 processed_transcript
  ENST00000534533 CTSH-014 78923059-78937233 processed_transcript
  ENST00000615999 CTSH-201 78922130-78944981 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000220166ENST00000525807ENST00000527138ENST00000527715ENST00000534038ENST00000534237ENST00000615999
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000220166 N/A N/A N/A N/A 1.452±0.00 N/A 0.646±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000525807 18.684±0.00 88.437±0.00 23.385±0.00 16.231±1.69 12.951±7.94 11.260±5.85 10.243±9.37 101.081±71.45 19.262±5.17 72.605±15.19 5.985±2.44 71.238±27.58 40.435±22.07 12.986±2.05
ENST00000527138 N/A N/A N/A N/A N/A 2.439±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000527715 N/A N/A N/A N/A N/A 1.139±0.00 0.310±0.00 N/A N/A 11.401±0.00 0.614±0.00 N/A N/A N/A
ENST00000534038 N/A N/A N/A N/A N/A N/A 7.885±7.10 N/A 14.286±0.00 N/A 4.407±0.04 39.767±0.00 39.338±0.00 N/A
ENST00000534237 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 97.458±0.00 32.620±0.00 22.461±0.00
ENST00000615999 N/A N/A N/A N/A N/A N/A 2.860±2.03 80.945±0.00 N/A 22.397±0.00 1.974±0.00 31.634±10.51 17.312±1.57 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001520 IEA outer dense fiber
GO:0001656 ISS metanephros development
GO:0001669 IEA acrosomal vesicle
GO:0001913 ISS T cell mediated cytotoxicity
GO:0002250 IEP adaptive immune response
GO:0002764 IDA immune response-regulating signaling pathway
GO:0004175 IDA endopeptidase activity
GO:0004177 IDA aminopeptidase activity
GO:0004197 TAS cysteine-type endopeptidase activity
GO:0004252 ISS serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005764 IDA lysosome
GO:0005829 IDA cytosol
GO:0005930 IEA axoneme
GO:0006508 TAS:IEA proteolysis
GO:0006915 IEA apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007283 IEA spermatogenesis
GO:0008233 IDA peptidase activity
GO:0008234 IDA:IEA cysteine-type peptidase activity
GO:0008284 ISS positive regulation of cell proliferation
GO:0008656 IDA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0010628 IDA positive regulation of gene expression
GO:0010634 ISS positive regulation of epithelial cell migration
GO:0010813 IDA neuropeptide catabolic process
GO:0010815 IDA bradykinin catabolic process
GO:0010952 IDA positive regulation of peptidase activity
GO:0016505 IEA peptidase activator activity involved in apoptotic process
GO:0019882 TAS antigen processing and presentation
GO:0030108 IDA HLA-A specific activating MHC class I receptor activity
GO:0030335 IDA positive regulation of cell migration
GO:0030984 IEA kininogen binding
GO:0031638 IDA zymogen activation
GO:0031648 IMP protein destabilization
GO:0032403 IEA protein complex binding
GO:0032526 ISS response to retinoic acid
GO:0033619 IDA membrane protein proteolysis
GO:0043066 ISS negative regulation of apoptotic process
GO:0043129 IDA surfactant homeostasis
GO:0043621 IEA protein self-association
GO:0045766 ISS positive regulation of angiogenesis
GO:0060448 ISS dichotomous subdivision of terminal units involved in lung branching
GO:0070062 IDA extracellular vesicular exosome
GO:0070324 IDA thyroid hormone binding
GO:0070371 IDA ERK1 and ERK2 cascade
GO:0097067 IEP cellular response to thyroid hormone stimulus
GO:0097208 IDA alveolar lamellar body
GO:2001235 IEA positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041108 ctsh cathepsin H protein_coding Danio_rerio
ENSMUSG00000032359 Ctsh cathepsin H protein_coding Mus_musculus

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