C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CD276 molecule
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103855 CD276 9606 + 15:73683966-73714518 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318424 CD276-201 73684281-73714509 protein_coding
  ENST00000318443 CD276-002 73684213-73714518 protein_coding
  ENST00000537340 CD276-007 73684269-73713677 protein_coding
  ENST00000557951 CD276-013 73703951-73708689 retained_intron
  ENST00000558689 CD276-014 73684383-73702585 protein_coding
  ENST00000559073 CD276-008 73704197-73714514 nonsense_mediated_decay
  ENST00000559465 CD276-009 73711132-73714514 retained_intron
  ENST00000559978 CD276-011 73709565-73714053 retained_intron
  ENST00000560786 CD276-021 73684383-73702821 protein_coding
  ENST00000560928 CD276-006 73684438-73713580 nonsense_mediated_decay
  ENST00000560995 CD276-016 73684731-73702573 protein_coding
  ENST00000561176 CD276-012 73703909-73712998 protein_coding
  ENST00000561213 CD276-003 73684391-73712154 protein_coding
  ENST00000561260 CD276-015 73685006-73702849 protein_coding
  ENST00000561416 CD276-017 73684502-73702330 protein_coding
  ENST00000563584 CD276-020 73684438-73702497 protein_coding
  ENST00000564751 CD276-001 73699640-73712956 protein_coding
  ENST00000567189 CD276-018 73683966-73702573 protein_coding
  ENST00000567582 CD276-019 73684772-73702952 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318424ENST00000318443ENST00000537340ENST00000557951ENST00000559073ENST00000559465ENST00000560928ENST00000561176ENST00000561213ENST00000564751
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318424 N/A N/A N/A N/A N/A 0.847±0.00 N/A N/A N/A N/A N/A 7.853±0.00 12.417±0.00 N/A
ENST00000318443 10.755±0.00 2.673±0.00 N/A N/A 5.734±0.00 N/A N/A 1.771±0.05 N/A N/A N/A 4.161±2.54 11.181±0.44 6.200±0.00
ENST00000537340 N/A N/A N/A 1.066±0.00 N/A 3.580±0.00 1.814±1.53 N/A 3.264±0.00 N/A N/A N/A N/A N/A
ENST00000557951 N/A N/A 0.698±0.00 N/A N/A N/A N/A 3.727±0.00 N/A N/A N/A N/A N/A N/A
ENST00000559073 N/A 3.316±0.00 N/A N/A 4.936±0.00 5.632±0.00 2.619±0.00 1.946±0.41 2.793±0.00 N/A 1.240±0.00 8.441±0.00 12.294±1.16 5.491±0.00
ENST00000559465 13.878±0.00 7.327±0.00 0.411±0.00 2.749±0.00 8.487±0.00 3.988±3.18 2.943±2.59 5.601±0.00 6.757±5.40 4.232±3.95 1.843±0.00 20.287±10.53 37.482±9.68 9.021±0.39
ENST00000560928 N/A N/A N/A N/A 2.076±0.00 1.113±0.00 0.343±0.00 2.273±0.00 1.839±0.00 0.744±0.00 0.720±0.11 6.907±4.43 18.786±0.00 2.295±0.00
ENST00000561176 N/A N/A 0.756±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 56.717±0.00 113.255±0.00 14.189±0.00
ENST00000561213 N/A N/A 0.093±0.00 0.620±0.00 N/A 0.388±0.00 N/A N/A N/A 0.136±0.00 0.448±0.00 N/A N/A N/A
ENST00000564751 N/A N/A N/A N/A N/A N/A 0.516±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 NAS receptor binding
GO:0005515 IPI:IEA protein binding
GO:0006955 NAS immune response
GO:0008283 NAS cell proliferation
GO:0009897 NAS external side of plasma membrane
GO:0016021 NAS integral component of membrane
GO:0030501 IEA positive regulation of bone mineralization
GO:0042102 IDA positive regulation of T cell proliferation
GO:0042110 IDA T cell activation
GO:0042130 IEA negative regulation of T cell proliferation
GO:0045077 IEA negative regulation of interferon-gamma biosynthetic process
GO:0045078 IDA positive regulation of interferon-gamma biosynthetic process
GO:0045085 IEA negative regulation of interleukin-2 biosynthetic process
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0050728 IEA negative regulation of inflammatory response
GO:0050776 NAS regulation of immune response
GO:0070062 IDA extracellular vesicular exosome
GO:1900042 IEA positive regulation of interleukin-2 secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003061 cd276 CD276 molecule protein_coding Danio_rerio
ENSMUSG00000035914 Cd276 CD276 antigen protein_coding Mus_musculus

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