C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CD276 antigen
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035914 Cd276 10090 - 9:58524300-58555132 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039788 Cd276-201 58524300-58540941 protein_coding
  ENSMUST00000165365 Cd276-202 58524302-58555132 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039788ENSMUST00000165365
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039788 1.015±0.00 2.280±1.28 1.104±0.12 1.794±0.00 2.026±1.61 3.148±1.31 1.997±0.00 0.367±0.15 0.559±0.35 1.407±0.44 1.394±0.50 4.326±1.97 1.277±1.02 0.111±0.02
ENSMUST00000165365 3.980±2.43 3.464±0.38 3.079±0.52 9.475±1.32 3.418±0.73 2.736±0.64 1.699±0.69 0.469±0.05 0.671±0.34 2.003±0.80 0.859±0.35 5.024±2.34 1.224±0.28 0.358±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00045S CIL_00045S_0002 CGP 9:58488603-58555132

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 IDA receptor binding
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0030501 IMP positive regulation of bone mineralization
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042110 IEA T cell activation
GO:0042130 IDA negative regulation of T cell proliferation
GO:0045077 IDA negative regulation of interferon-gamma biosynthetic process
GO:0045078 IEA positive regulation of interferon-gamma biosynthetic process
GO:0045085 IDA negative regulation of interleukin-2 biosynthetic process
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0050728 IMP negative regulation of inflammatory response
GO:0050776 IMP regulation of immune response
GO:0070062 IEA extracellular vesicular exosome
GO:1900042 IMP positive regulation of interleukin-2 secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003061 cd276 CD276 molecule protein_coding Danio_rerio
ENSG00000103855 CD276 CD276 molecule protein_coding Homo_sapiens

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