C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: carbonic anhydrase II
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104267 CA2 9606 + 8:85463852-85481493 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000285379 CA2-001 85463852-85481493 protein_coding
  ENST00000518231 CA2-004 85464011-85473976 retained_intron
  ENST00000520127 CA2-002 85463968-85480886 nonsense_mediated_decay
  ENST00000520996 CA2-003 85464003-85474577 retained_intron
  ENST00000522742 CA2-005 85464014-85477155 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000285379ENST00000518231ENST00000520127ENST00000520996
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000285379 1.174±0.00 0.478±0.00 12.929±0.00 7.128±2.78 1.917±0.36 46.274±39.70 0.386±0.22 41.148±26.41 10.756±0.00 6.912±0.70 1.566±1.01 1.687±1.48 7.196±1.46 2.364±0.55
ENST00000518231 N/A N/A N/A N/A N/A N/A 0.560±0.00 N/A 0.083±0.00 N/A N/A N/A N/A N/A
ENST00000520127 0.935±0.00 0.880±0.00 8.798±0.00 10.566±4.36 1.938±0.00 5.355±0.00 3.259±0.00 124.130±0.00 10.103±9.68 22.180±0.00 3.860±0.00 1.514±0.98 5.087±0.00 19.025±1.24
ENST00000520996 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.474±0.00 N/A N/A 17.882±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SZ CIL_0006SZ_0001 CGP 8:85373436-85481493

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IEA kidney development
GO:0002009 IEA morphogenesis of an epithelium
GO:0004089 IEA carbonate dehydratase activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005902 IEA microvillus
GO:0006730 IEA one-carbon metabolic process
GO:0008270 IDA zinc ion binding
GO:0009268 IEA response to pH
GO:0010033 IEA response to organic substance
GO:0010043 IEA response to zinc ion
GO:0015701 TAS bicarbonate transport
GO:0016323 IEA basolateral plasma membrane
GO:0030424 IEA axon
GO:0032230 IEA positive regulation of synaptic transmission, GABAergic
GO:0032849 IEA positive regulation of cellular pH reduction
GO:0038166 IDA angiotensin-activated signaling pathway
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043209 IEA myelin sheath
GO:0043627 IEA response to estrogen
GO:0044070 IDA regulation of anion transport
GO:0044281 TAS small molecule metabolic process
GO:0045177 IDA apical part of cell
GO:0045672 IEA positive regulation of osteoclast differentiation
GO:0045780 IEA positive regulation of bone resorption
GO:0046903 IEA secretion
GO:0048545 IEA response to steroid hormone
GO:0051453 ISS regulation of intracellular pH
GO:0070062 IDA extracellular vesicular exosome
GO:0071498 IEA cellular response to fluid shear stress
GO:2001150 ISS positive regulation of dipeptide transmembrane transport
GO:2001225 IEA regulation of chloride transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011166 cahz carbonic anhydrase protein_coding Danio_rerio
ENSDARG00000014488 ca2 carbonic anhydrase II protein_coding Danio_rerio
ENSMUSG00000027562 Car2 carbonic anhydrase 2 protein_coding Mus_musculus

Loading