C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: carbonic anhydrase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027562 Car2 10090 + 3:14886426-14900769 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029078 Car2-201 14886426-14900769 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029078
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029078 8.173±8.27 25.267±4.46 2.967±0.03 27.058±32.83 4.081±0.51 170.255±108.38 2.918±1.48 273.446±44.57 315.282±357.03 35.544±4.26 3.167±0.65 16.778±5.82 449.683±276.98 55.361±20.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SZ CIL_0006SZ_0002 CGP 3:14863538-14900769

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IEA kidney development
GO:0002009 IMP morphogenesis of an epithelium
GO:0004089 IDA carbonate dehydratase activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005737 ISS cytoplasm
GO:0005829 IDA cytosol
GO:0005886 ISS plasma membrane
GO:0005902 IEA microvillus
GO:0006730 IEA one-carbon metabolic process
GO:0006885 IC regulation of pH
GO:0008270 IEA zinc ion binding
GO:0009268 IEA response to pH
GO:0010033 IEA response to organic substance
GO:0010043 IEA response to zinc ion
GO:0015670 IC carbon dioxide transport
GO:0016323 IEA basolateral plasma membrane
GO:0030424 IEA axon
GO:0032230 IGI positive regulation of synaptic transmission, GABAergic
GO:0032849 IMP positive regulation of cellular pH reduction
GO:0038166 ISS angiotensin-activated signaling pathway
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043209 IDA myelin sheath
GO:0043627 IEA response to estrogen
GO:0044070 ISS regulation of anion transport
GO:0045177 IEA apical part of cell
GO:0045672 IEA positive regulation of osteoclast differentiation
GO:0045780 IEA positive regulation of bone resorption
GO:0046903 IMP secretion
GO:0048545 IEA response to steroid hormone
GO:0051453 IMP regulation of intracellular pH
GO:0070062 IEA extracellular vesicular exosome
GO:0071498 IEA cellular response to fluid shear stress
GO:2001150 IMP positive regulation of dipeptide transmembrane transport
GO:2001225 IMP regulation of chloride transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011166 cahz carbonic anhydrase protein_coding Danio_rerio
ENSDARG00000014488 ca2 carbonic anhydrase II protein_coding Danio_rerio
ENSG00000104267 CA2 carbonic anhydrase II protein_coding Homo_sapiens

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