C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: frizzled class receptor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104290 FZD3 9606 + 8:28494205-28574268 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000240093 FZD3-001 28494256-28574268 protein_coding
  ENST00000517911 FZD3-003 28563063-28563981 processed_transcript
  ENST00000523546 FZD3-002 28494214-28503119 protein_coding
  ENST00000537916 FZD3-201 28494205-28574267 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000240093ENST00000523546ENST00000537916
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000240093 N/A N/A 1.502±0.49 N/A 0.426±0.00 0.099±0.00 0.039±0.00 0.077±0.00 0.788±0.00 0.001±0.00 0.334±0.18 0.183±0.00 1.175±0.09
ENST00000523546 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.591±0.00 N/A 0.566±0.00 N/A
ENST00000537916 0.251±0.00 0.448±0.00 1.990±0.00 0.523±0.27 0.416±0.25 0.159±0.06 0.360±0.32 1.432±0.00 0.191±0.00 0.059±0.06 0.592±0.00 0.363±0.22 1.049±0.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000935 CIL_000935_0001 VISTA 8:28213350-28814343
CIL_00013A CIL_00013A_0002 CGP 8:28348287-28574268

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001736 IBA establishment of planar polarity
GO:0001764 IEA neuron migration
GO:0001843 IBA neural tube closure
GO:0001942 IEA hair follicle development
GO:0001944 IBA vasculature development
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007199 IBA G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0008406 IBA gonad development
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0016328 IEA lateral plasma membrane
GO:0017147 IPI Wnt-protein binding
GO:0021754 IBA facial nucleus development
GO:0030165 IPI PDZ domain binding
GO:0030182 ISS neuron differentiation
GO:0030424 IBA axon
GO:0030425 IBA dendrite
GO:0030901 IEA midbrain development
GO:0032589 IBA neuron projection membrane
GO:0033278 IBA cell proliferation in midbrain
GO:0036342 IEA post-anal tail morphogenesis
GO:0042472 IBA inner ear morphogenesis
GO:0042813 IBA Wnt-activated receptor activity
GO:0043025 IBA neuronal cell body
GO:0045177 IBA apical part of cell
GO:0048786 IBA presynaptic active zone
GO:0060070 IDA canonical Wnt signaling pathway
GO:0071679 IBA commissural neuron axon guidance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021664 fzd3a frizzled homolog 3a protein_coding Danio_rerio
ENSMUSG00000007989 Fzd3 frizzled homolog 3 (Drosophila) protein_coding Mus_musculus

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