C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: plasminogen activator, tissue
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104368 PLAT 9606 - 8:42175233-42207724 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000220809 PLAT-001 42175233-42207724 protein_coding
  ENST00000352041 PLAT-002 42175237-42207676 protein_coding
  ENST00000429089 PLAT-003 42175233-42207565 protein_coding
  ENST00000429710 PLAT-006 42175747-42207565 protein_coding
  ENST00000519510 PLAT-005 42175561-42207565 protein_coding
  ENST00000520523 PLAT-012 42187401-42193727 protein_coding
  ENST00000521042 PLAT-008 42180306-42187932 nonsense_mediated_decay
  ENST00000521647 PLAT-013 42184695-42188489 retained_intron
  ENST00000521694 PLAT-011 42187465-42195698 protein_coding
  ENST00000522812 PLAT-010 42180083-42180764 retained_intron
  ENST00000524009 PLAT-004 42175900-42207565 protein_coding
  ENST00000524261 PLAT-009 42182340-42185113 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000220809ENST00000352041ENST00000429089ENST00000429710ENST00000519510ENST00000521042ENST00000521647ENST00000521694ENST00000524009
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000220809 4.750±0.00 21.364±0.00 3.256±0.00 3.711±0.00 3.432±0.00 7.281±5.36 3.877±0.00 49.632±0.00 18.434±0.00 5.083±2.36 N/A 15.164±9.19 N/A 11.507±0.00
ENST00000352041 N/A N/A N/A 0.298±0.00 5.961±2.00 N/A 0.602±0.00 0.089±0.00 N/A 18.876±0.00 N/A 7.418±0.00 5.945±2.96 3.469±1.02
ENST00000429089 1.965±0.00 N/A N/A 2.101±1.87 8.359±0.00 6.381±0.00 N/A 40.791±0.00 N/A N/A 2.431±0.00 N/A N/A N/A
ENST00000429710 N/A N/A N/A 4.054±0.00 N/A 3.131±0.00 N/A 0.460±0.00 N/A 1.285±0.00 N/A N/A N/A 1.930±0.00
ENST00000519510 N/A N/A 2.386±0.00 0.626±0.00 4.144±0.00 4.406±1.60 0.846±0.27 43.686±0.00 9.066±0.00 21.477±0.00 1.035±0.00 N/A 3.321±0.00 2.069±0.00
ENST00000521042 N/A N/A N/A N/A N/A N/A N/A 1.168±0.00 N/A N/A N/A N/A N/A N/A
ENST00000521647 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.683±0.00 N/A N/A
ENST00000521694 N/A N/A N/A N/A N/A N/A N/A 0.574±0.00 N/A N/A N/A N/A N/A N/A
ENST00000524009 2.390±0.00 N/A N/A N/A 6.912±0.00 N/A N/A 0.344±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007IG CIL_0007IG_0002 CGP 8:42175233-42332653

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0003824 IEA catalytic activity
GO:0004252 IDA:IEA serine-type endopeptidase activity
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0005737 IDA cytoplasm
GO:0006464 TAS cellular protein modification process
GO:0006508 IEA proteolysis
GO:0007596 TAS blood coagulation
GO:0009986 IDA cell surface
GO:0014909 IEA smooth muscle cell migration
GO:0030141 IEA secretory granule
GO:0031639 IDA plasminogen activation
GO:0035249 IEA synaptic transmission, glutamatergic
GO:0042060 IEA wound healing
GO:0042730 TAS fibrinolysis
GO:0043434 IEA response to peptide hormone
GO:0045177 IEA apical part of cell
GO:0045202 IEA synapse
GO:0045861 IDA negative regulation of proteolysis
GO:0048008 IEA platelet-derived growth factor receptor signaling pathway
GO:0048167 IEA regulation of synaptic plasticity
GO:0051591 IEA response to cAMP
GO:0060279 IEA positive regulation of ovulation
GO:0070062 IDA extracellular vesicular exosome
GO:0071549 IEA cellular response to dexamethasone stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062707 plat plasminogen activator, tissue protein_coding Danio_rerio
ENSMUSG00000031538 Plat plasminogen activator, tissue protein_coding Mus_musculus

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