C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104783 KCNN4 9606 - 19:43766533-43781257 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262888 KCNN4-001 43766533-43781257 protein_coding
  ENST00000597184 KCNN4-012 43766822-43769157 retained_intron
  ENST00000598836 KCNN4-010 43766586-43769827 protein_coding
  ENST00000599107 KCNN4-008 43774219-43776826 retained_intron
  ENST00000599720 KCNN4-007 43766953-43780976 nonsense_mediated_decay
  ENST00000600408 KCNN4-009 43767577-43772107 nonsense_mediated_decay
  ENST00000600909 KCNN4-013 43766533-43768977 protein_coding
  ENST00000601549 KCNN4-011 43767452-43772127 retained_intron
  ENST00000615047 KCNN4-201 43766533-43781257 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262888ENST00000597184ENST00000598836ENST00000599107ENST00000599720ENST00000600408ENST00000600909ENST00000601549ENST00000615047
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262888 N/A 4.700±0.00 0.407±0.00 3.310±0.00 0.402±0.00 N/A 0.228±0.00 0.104±0.00 3.232±0.00 N/A 0.607±0.20 20.855±15.28 N/A
ENST00000597184 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.694±0.00 N/A 0.518±0.26
ENST00000598836 0.430±0.00 N/A N/A N/A 0.931±0.00 N/A N/A N/A N/A N/A 2.310±0.00 17.289±0.00 0.904±0.00
ENST00000599107 N/A N/A N/A N/A N/A N/A N/A 0.605±0.00 N/A N/A N/A N/A N/A
ENST00000599720 N/A N/A N/A 2.405±1.95 1.890±1.07 0.070±0.00 N/A N/A N/A N/A 0.418±0.27 8.958±0.00 0.261±0.00
ENST00000600408 0.199±0.00 N/A N/A N/A N/A 0.306±0.00 N/A 0.034±0.00 N/A N/A 1.100±0.00 N/A 0.689±0.00
ENST00000600909 N/A 3.232±0.00 0.354±0.00 N/A 1.547±0.00 0.043±0.00 0.267±0.00 N/A N/A 0.872±0.82 0.739±0.34 N/A 0.089±0.00
ENST00000601549 N/A N/A N/A 0.729±0.00 N/A N/A 0.064±0.00 0.071±0.00 N/A N/A 0.394±0.00 N/A N/A
ENST00000615047 0.094±0.00 N/A N/A N/A N/A 0.041±0.02 N/A N/A 0.256±0.00 N/A 0.210±0.13 4.784±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002376 IEA immune system process
GO:0005267 IEA potassium channel activity
GO:0005515 IPI protein binding
GO:0005516 IEA:IBA calmodulin binding
GO:0005886 IBA plasma membrane
GO:0006813 TAS:IEA potassium ion transport
GO:0006816 IDA calcium ion transport
GO:0006820 IEA anion transport
GO:0006884 IEA cell volume homeostasis
GO:0006952 TAS defense response
GO:0007268 TAS synaptic transmission
GO:0008076 IC voltage-gated potassium channel complex
GO:0015269 IDA:IEA calcium-activated potassium channel activity
GO:0016021 IEA integral component of membrane
GO:0016286 IEA small conductance calcium-activated potassium channel activity
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019903 IPI protein phosphatase binding
GO:0022894 IBA Intermediate conductance calcium-activated potassium channel activity
GO:0030322 IDA stabilization of membrane potential
GO:0043025 IBA neuronal cell body
GO:0045121 IEA membrane raft
GO:0045332 IEA phospholipid translocation
GO:0046541 IEA saliva secretion
GO:0050714 IEA positive regulation of protein secretion
GO:0050862 IDA positive regulation of T cell receptor signaling pathway
GO:0071435 IEA potassium ion export
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086091 KCNN4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 protein_coding Danio_rerio
ENSMUSG00000054342 Kcnn4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 protein_coding Mus_musculus

Loading