C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054342 Kcnn4 10090 + 7:24370263-24385209 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000171904 Kcnn4-201 24370263-24385209 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000171904
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000171904 1.767±0.62 0.793±0.11 16.009±3.86 0.154±0.05 10.525±4.60 32.298±10.78 0.283±0.20 0.779±0.43 29.639±33.71 2.415±0.87 0.143±0.06 4.029±1.71 1.101±0.86 0.441±0.24

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002376 IEA immune system process
GO:0005267 IGI potassium channel activity
GO:0005515 IEA protein binding
GO:0005516 IBA calmodulin binding
GO:0005886 IBA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006816 IEA calcium ion transport
GO:0006820 IEA anion transport
GO:0006884 IMP cell volume homeostasis
GO:0015269 IDA calcium-activated potassium channel activity
GO:0016286 IEA small conductance calcium-activated potassium channel activity
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019903 IEA protein phosphatase binding
GO:0022894 IBA Intermediate conductance calcium-activated potassium channel activity
GO:0030322 IEA stabilization of membrane potential
GO:0043025 IBA neuronal cell body
GO:0045121 IEA membrane raft
GO:0045332 IMP phospholipid translocation
GO:0046541 IGI saliva secretion
GO:0050714 IDA positive regulation of protein secretion
GO:0050862 IEA positive regulation of T cell receptor signaling pathway
GO:0071435 IEA potassium ion export

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086091 KCNN4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 protein_coding Danio_rerio
ENSG00000104783 KCNN4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 protein_coding Homo_sapiens

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