C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105137 SYDE1 9606 + 19:15107403-15114988 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342784 SYDE1-001 15107403-15114988 protein_coding
  ENST00000597977 SYDE1-004 15107405-15109477 protein_coding
  ENST00000600252 SYDE1-003 15108833-15114974 protein_coding
  ENST00000600440 SYDE1-002 15107405-15114985 protein_coding
  ENST00000602203 SYDE1-005 15110581-15113622 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342784ENST00000600440
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342784 8.683±0.00 7.311±0.00 2.775±0.00 10.627±0.00 6.696±0.00 5.900±0.00 6.538±0.00 1.242±0.00 4.737±0.00 2.021±0.00 25.906±12.35 26.434±10.01 9.010±0.00
ENST00000600440 6.670±0.00 14.121±0.00 N/A N/A 9.240±0.00 0.509±0.00 6.408±0.00 N/A 5.991±0.00 N/A 9.488±0.00 17.952±3.67 7.355±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005096 IEA GTPase activator activity
GO:0005100 ISS Rho GTPase activator activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0007130 IEA synaptonemal complex assembly
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0016081 IEA synaptic vesicle docking involved in exocytosis
GO:0032403 IEA protein complex binding
GO:0032862 ISS activation of Rho GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0044300 IEA cerebellar mossy fiber
GO:0050806 IEA positive regulation of synaptic transmission
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097060 IEA synaptic membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077440 SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) protein_coding Danio_rerio
ENSMUSG00000032714 Syde1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) protein_coding Mus_musculus

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