C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105197 TIMM50 9606 + 19:39480412-39493785 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000314349 TIMM50-001 39480412-39489928 protein_coding
  ENST00000544017 TIMM50-201 39480412-39490888 protein_coding
  ENST00000594583 TIMM50-017 39481225-39486495 protein_coding
  ENST00000595286 TIMM50-013 39480858-39483545 retained_intron
  ENST00000595527 TIMM50-007 39491512-39493785 retained_intron
  ENST00000595961 TIMM50-003 39485591-39491230 retained_intron
  ENST00000596239 TIMM50-018 39485039-39485806 retained_intron
  ENST00000597552 TIMM50-019 39488006-39489768 retained_intron
  ENST00000597666 TIMM50-010 39480850-39488174 protein_coding
  ENST00000597782 TIMM50-014 39480882-39485602 nonsense_mediated_decay
  ENST00000598125 TIMM50-009 39480846-39483194 retained_intron
  ENST00000599733 TIMM50-015 39480928-39486495 nonsense_mediated_decay
  ENST00000599794 TIMM50-008 39480841-39490119 protein_coding
  ENST00000600878 TIMM50-020 39492417-39493715 processed_transcript
  ENST00000601252 TIMM50-005 39488114-39492722 nonsense_mediated_decay
  ENST00000601358 TIMM50-002 39480484-39489928 nonsense_mediated_decay
  ENST00000601403 TIMM50-011 39480853-39488186 protein_coding
  ENST00000602028 TIMM50-012 39480856-39488217 protein_coding
  ENST00000602265 TIMM50-016 39480928-39488604 nonsense_mediated_decay
  ENST00000607714 TIMM50-021 39480832-39490074 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000544017ENST00000594583ENST00000595527ENST00000595961ENST00000597666ENST00000599794ENST00000600878ENST00000601252ENST00000601358ENST00000601403ENST00000602265ENST00000607714
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000544017 N/A N/A N/A N/A N/A N/A N/A 0.912±0.00 N/A N/A N/A N/A N/A N/A
ENST00000594583 17.663±0.00 N/A N/A N/A N/A 8.577±0.00 12.464±0.00 N/A N/A N/A N/A N/A N/A 27.118±0.00
ENST00000595527 3.858±0.00 4.888±0.00 N/A 6.966±0.00 6.015±0.00 2.325±0.00 1.410±1.16 3.147±2.86 1.223±1.06 N/A N/A 5.439±0.70 N/A N/A
ENST00000595961 N/A N/A 0.515±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.553±0.00 N/A N/A
ENST00000597666 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.753±0.00 7.046±0.00 N/A N/A N/A
ENST00000599794 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.611±0.00 N/A N/A N/A
ENST00000600878 N/A N/A N/A N/A 0.535±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000601252 N/A N/A 1.085±0.00 4.810±3.26 0.268±0.00 1.464±1.16 N/A N/A 0.881±0.00 0.155±0.00 N/A 4.915±2.83 N/A N/A
ENST00000601358 N/A N/A N/A N/A N/A 0.909±0.00 0.848±0.00 N/A N/A N/A 2.428±0.00 N/A N/A N/A
ENST00000601403 N/A 19.114±0.00 N/A N/A N/A 8.652±0.00 N/A N/A N/A N/A N/A 38.939±0.00 18.919±0.00 45.955±2.95
ENST00000602265 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.582±0.00 10.987±0.00 26.796±0.00
ENST00000607714 20.874±0.00 27.387±0.00 N/A 11.684±6.95 15.049±13.79 5.411±4.60 11.692±9.77 9.255±6.59 8.820±7.51 21.272±0.00 40.936±0.00 22.104±12.49 24.768±7.41 40.948±12.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001836 IDA release of cytochrome c from mitochondria
GO:0003723 IEA RNA binding
GO:0004721 IDA phosphoprotein phosphatase activity
GO:0004722 IDA protein serine/threonine phosphatase activity
GO:0004725 IDA protein tyrosine phosphatase activity
GO:0005134 IDA interleukin-2 receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005744 IPI mitochondrial inner membrane presequence translocase complex
GO:0006470 IDA protein dephosphorylation
GO:0006626 TAS protein targeting to mitochondrion
GO:0007006 IMP mitochondrial membrane organization
GO:0015031 IEA protein transport
GO:0016021 IEA integral component of membrane
GO:0016607 IDA nuclear speck
GO:0035335 IDA peptidyl-tyrosine dephosphorylation
GO:0043021 IDA ribonucleoprotein complex binding
GO:0044267 TAS cellular protein metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031098 timm50 translocase of inner mitochondrial membrane 50 homolog (yeast) protein_coding Danio_rerio
ENSMUSG00000003438 Timm50 translocase of inner mitochondrial membrane 50 protein_coding Mus_musculus

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