C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105204 DYRK1B 9606 - 19:39825350-39834201 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000323039 DYRK1B-001 39825350-39834201 protein_coding
  ENST00000348817 DYRK1B-201 39825353-39834201 protein_coding
  ENST00000430012 DYRK1B-007 39825715-39834158 protein_coding
  ENST00000593685 DYRK1B-006 39825350-39833634 protein_coding
  ENST00000597639 DYRK1B-008 39825715-39831867 protein_coding
  ENST00000600611 DYRK1B-005 39829882-39833638 protein_coding
  ENST00000601696 DYRK1B-004 39828402-39830143 retained_intron
  ENST00000601972 DYRK1B-003 39830206-39834152 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000323039ENST00000348817ENST00000430012ENST00000593685ENST00000597639ENST00000600611ENST00000601696ENST00000601972
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000323039 N/A N/A N/A 1.803±0.62 N/A N/A 5.133±0.00 1.503±0.00 N/A 2.527±0.00 6.314±0.00 3.435±1.42 3.502±0.50 6.113±0.00
ENST00000348817 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.496±0.00 2.458±0.13 N/A
ENST00000430012 2.208±0.00 2.179±0.00 N/A 3.567±1.91 5.862±0.00 0.508±0.22 2.901±0.00 3.149±0.00 0.742±0.00 0.578±0.00 12.233±1.10 3.966±3.37 3.619±0.00 42.845±19.60
ENST00000593685 0.768±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.449±0.63
ENST00000597639 0.951±0.00 N/A 0.148±0.00 N/A 0.497±0.00 0.057±0.00 2.100±0.00 N/A N/A N/A 20.283±0.00 2.116±1.51 1.190±0.00 13.900±0.00
ENST00000600611 N/A N/A N/A N/A 0.592±0.00 0.514±0.00 0.526±0.00 N/A N/A N/A N/A 7.837±0.00 2.326±0.00 48.873±0.00
ENST00000601696 N/A N/A N/A N/A 0.399±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000601972 N/A N/A N/A N/A N/A N/A 0.964±0.00 N/A 0.926±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003713 IDA transcription coactivator activity
GO:0004672 IEA:IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0006468 IEA:IDA protein phosphorylation
GO:0007520 IEA myoblast fusion
GO:0008152 IEA metabolic process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0060612 IMP adipose tissue development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070187 dyrk1b dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B protein_coding Danio_rerio
ENSMUSG00000002409 Dyrk1b dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b protein_coding Mus_musculus

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