C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002409 Dyrk1b 10090 + 7:28179469-28187294 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085901 Dyrk1b-001 28179469-28187294 protein_coding
  ENSMUST00000172467 Dyrk1b-004 28180266-28187294 protein_coding
  ENSMUST00000172761 Dyrk1b-003 28179494-28186923 protein_coding
  ENSMUST00000173223 Dyrk1b-002 28180316-28186943 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000085901ENSMUST00000172467ENSMUST00000172761ENSMUST00000173223
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000085901 3.635±0.82 15.587±4.04 N/A 11.801±4.78 7.845±1.08 3.181±0.20 5.981±1.37 2.163±0.62 8.735±1.71 9.416±4.05 11.115±1.11 3.546±2.86 N/A
ENSMUST00000172467 4.807±1.87 7.831±0.00 N/A 12.612±0.21 N/A 2.614±0.06 1.233±0.26 1.165±0.70 3.012±0.00 9.584±1.89 1.643±0.00 1.562±0.69 80.174±8.36
ENSMUST00000172761 6.606±0.60 9.105±2.41 17.170±0.00 9.511±3.52 4.425±1.42 4.356±1.71 4.040±1.40 1.174±0.41 7.547±1.39 4.871±1.54 5.975±1.57 5.001±5.56 97.396±14.28
ENSMUST00000173223 N/A N/A N/A N/A N/A 3.022±0.00 N/A N/A N/A N/A 15.782±0.00 3.716±0.00 48.000±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003713 IEA transcription coactivator activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0007520 IMP myoblast fusion
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0060612 ISS adipose tissue development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070187 dyrk1b dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B protein_coding Danio_rerio
ENSG00000105204 DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B protein_coding Homo_sapiens

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