C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase D family, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105223 PLD3 9606 + 19:40348456-40380439 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356508 PLD3-004 40348700-40378483 protein_coding
  ENST00000359274 PLD3-012 40365994-40370011 protein_coding
  ENST00000392032 PLD3-007 40348584-40367836 protein_coding
  ENST00000409281 PLD3-006 40359642-40378483 protein_coding
  ENST00000409419 PLD3-001 40348678-40378475 protein_coding
  ENST00000409587 PLD3-003 40348685-40378483 protein_coding
  ENST00000409735 PLD3-002 40348690-40378483 protein_coding
  ENST00000464586 PLD3-010 40366293-40366644 retained_intron
  ENST00000475983 PLD3-013 40371477-40374814 retained_intron
  ENST00000480030 PLD3-011 40369909-40370892 retained_intron
  ENST00000485448 PLD3-005 40366438-40367844 retained_intron
  ENST00000486134 PLD3-015 40377860-40380439 nonsense_mediated_decay
  ENST00000488311 PLD3-014 40376267-40378127 retained_intron
  ENST00000492243 PLD3-008 40366880-40371818 nonsense_mediated_decay
  ENST00000493006 PLD3-009 40365895-40367263 retained_intron
  ENST00000594085 PLD3-024 40348690-40366464 processed_transcript
  ENST00000594908 PLD3-023 40348704-40370200 protein_coding
  ENST00000596470 PLD3-026 40371792-40378381 protein_coding
  ENST00000596682 PLD3-020 40348704-40366915 protein_coding
  ENST00000598962 PLD3-022 40348672-40366666 protein_coding
  ENST00000599353 PLD3-017 40367710-40370228 protein_coding
  ENST00000599685 PLD3-018 40348456-40366880 protein_coding
  ENST00000600479 PLD3-021 40348507-40366464 processed_transcript
  ENST00000600948 PLD3-025 40348700-40366803 protein_coding
  ENST00000602131 PLD3-019 40348690-40367809 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356508ENST00000409281ENST00000409419ENST00000409735ENST00000486134ENST00000492243ENST00000594908ENST00000596470
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356508 N/A N/A 2.937±0.00 24.611±0.00 N/A 2.687±0.00 34.158±0.00 23.108±0.00 8.468±2.30 15.669±8.62 3.173±0.00 48.140±38.13 74.097±40.59 N/A
ENST00000409281 N/A N/A N/A 23.995±0.00 1.505±0.00 N/A 5.051±0.00 7.178±0.00 4.383±0.00 4.162±0.00 N/A 4.251±0.00 N/A N/A
ENST00000409419 N/A 22.614±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 22.215±0.00 116.793±0.00 N/A N/A
ENST00000409735 70.995±0.00 44.754±0.00 N/A 119.015±0.00 47.861±46.18 59.353±0.00 43.867±0.00 39.801±0.00 22.287±0.00 48.549±45.70 26.028±0.00 88.598±36.41 61.181±32.32 84.990±0.00
ENST00000486134 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 139.883±0.00 N/A
ENST00000492243 N/A N/A N/A N/A 3.314±0.00 N/A N/A N/A N/A N/A N/A N/A 57.755±0.00 N/A
ENST00000594908 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 30.520±0.00 N/A
ENST00000596470 73.089±0.00 89.942±0.00 N/A 117.104±0.00 107.229±0.00 71.093±0.00 N/A 41.042±0.00 31.620±0.00 78.987±0.00 6.893±0.00 47.052±39.42 100.661±15.90 107.992±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004630 IEA phospholipase D activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0006644 TAS phospholipid metabolic process
GO:0006655 TAS phosphatidylglycerol biosynthetic process
GO:0008152 IEA metabolic process
GO:0008219 IEA cell death
GO:0016021 IEA integral component of membrane
GO:0016042 IEA lipid catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0070062 IDA extracellular vesicular exosome
GO:0070290 IEA N-acylphosphatidylethanolamine-specific phospholipase D activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068199 pld3 phospholipase D family, member 3 protein_coding Danio_rerio
ENSMUSG00000003363 Pld3 phospholipase D family, member 3 protein_coding Mus_musculus

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