C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase A2, group IVC (cytosolic, calcium-independent)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105499 PLA2G4C 9606 - 19:48047843-48110817 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354276 PLA2G4C-005 48047844-48110782 protein_coding
  ENST00000593765 PLA2G4C-021 48074438-48085110 retained_intron
  ENST00000594156 PLA2G4C-011 48099798-48110813 processed_transcript
  ENST00000594790 PLA2G4C-006 48047846-48055059 retained_intron
  ENST00000595161 PLA2G4C-024 48061360-48074837 protein_coding
  ENST00000595487 PLA2G4C-007 48099744-48110561 nonsense_mediated_decay
  ENST00000595899 PLA2G4C-014 48099772-48110563 processed_transcript
  ENST00000596138 PLA2G4C-009 48105334-48110746 protein_coding
  ENST00000596352 PLA2G4C-010 48099782-48110563 protein_coding
  ENST00000596353 PLA2G4C-023 48054890-48067931 retained_intron
  ENST00000596510 PLA2G4C-003 48051797-48073051 processed_transcript
  ENST00000597377 PLA2G4C-015 48097022-48100006 retained_intron
  ENST00000597713 PLA2G4C-016 48095464-48098237 nonsense_mediated_decay
  ENST00000598185 PLA2G4C-019 48074846-48090603 retained_intron
  ENST00000598457 PLA2G4C-018 48090194-48099757 retained_intron
  ENST00000598488 PLA2G4C-008 48105403-48110563 nonsense_mediated_decay
  ENST00000598813 PLA2G4C-013 48103420-48110563 processed_transcript
  ENST00000599063 PLA2G4C-002 48097765-48110767 retained_intron
  ENST00000599111 PLA2G4C-001 48047843-48110817 protein_coding
  ENST00000599239 PLA2G4C-022 48061632-48096937 processed_transcript
  ENST00000599300 PLA2G4C-020 48054922-48090409 protein_coding
  ENST00000599921 PLA2G4C-004 48048343-48110812 protein_coding
  ENST00000600170 PLA2G4C-012 48104032-48105481 retained_intron
  ENST00000601946 PLA2G4C-017 48062122-48098208 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354276ENST00000593765ENST00000594790ENST00000596353ENST00000597377ENST00000597713ENST00000598457ENST00000598813ENST00000599063ENST00000599111ENST00000599300ENST00000599921ENST00000601946
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354276 0.775±0.00 N/A N/A 1.932±0.00 0.323±0.00 3.915±0.00 1.118±0.00 0.087±0.00 N/A 8.117±5.33 2.960±0.55 1.348±0.64 1.563±0.00
ENST00000593765 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.697±0.00 N/A N/A
ENST00000594790 2.389±0.00 11.415±0.00 11.217±0.00 7.508±0.00 3.173±0.00 N/A 2.863±0.00 0.202±0.00 3.575±0.00 16.950±0.00 3.288±0.14 2.418±0.00 2.721±0.52
ENST00000596353 N/A N/A N/A N/A N/A N/A 2.215±0.00 N/A N/A N/A N/A N/A N/A
ENST00000597377 N/A N/A 10.137±0.00 N/A 2.759±0.00 4.302±0.00 N/A 6.390±0.00 N/A 8.665±0.00 1.629±0.00 N/A N/A
ENST00000597713 N/A N/A N/A N/A N/A N/A N/A 0.465±0.00 N/A N/A N/A N/A N/A
ENST00000598457 N/A N/A N/A N/A 2.279±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000598813 N/A N/A N/A N/A N/A N/A N/A 0.826±0.00 N/A N/A N/A N/A N/A
ENST00000599063 N/A N/A N/A N/A N/A N/A N/A 0.205±0.00 0.990±0.00 N/A N/A N/A N/A
ENST00000599111 0.702±0.00 3.964±0.00 4.368±2.98 2.047±0.00 2.592±0.00 2.026±0.00 N/A N/A N/A 6.639±0.00 0.728±0.44 2.453±1.05 0.654±0.00
ENST00000599300 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.750±0.00
ENST00000599921 N/A N/A 5.137±0.00 0.980±0.00 N/A 2.416±0.25 N/A 1.008±0.89 N/A 11.467±0.00 0.950±0.00 1.225±0.00 N/A
ENST00000601946 N/A N/A N/A N/A N/A 3.689±0.00 3.003±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004620 IEA phospholipase activity
GO:0005543 NAS phospholipid binding
GO:0005635 IEA nuclear envelope
GO:0005654 IEA nucleoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005829 TAS cytosol
GO:0005938 IEA cell cortex
GO:0006644 TAS phospholipid metabolic process
GO:0006954 NAS inflammatory response
GO:0007567 NAS parturition
GO:0008152 IEA metabolic process
GO:0009395 IEA phospholipid catabolic process
GO:0016020 TAS membrane
GO:0019369 NAS arachidonic acid metabolic process
GO:0035556 NAS intracellular signal transduction
GO:0036149 TAS phosphatidylinositol acyl-chain remodeling
GO:0036151 TAS phosphatidylcholine acyl-chain remodeling
GO:0036152 TAS phosphatidylethanolamine acyl-chain remodeling
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0046475 IDA glycerophospholipid catabolic process
GO:0047499 IDA calcium-independent phospholipase A2 activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033355 PLA2G4C (1 of 5) phospholipase A2, group IVC (cytosolic, calcium-independent) protein_coding Danio_rerio
ENSDARG00000036713 PLA2G4C (2 of 5) phospholipase A2, group IVC (cytosolic, calcium-independent) protein_coding Danio_rerio
ENSDARG00000042090 PLA2G4C (3 of 5) phospholipase A2, group IVC (cytosolic, calcium-independent) protein_coding Danio_rerio
ENSDARG00000045982 PLA2G4C (4 of 5) phospholipase A2, group IVC (cytosolic, calcium-independent) protein_coding Danio_rerio
ENSDARG00000091765 PLA2G4C (5 of 5) phospholipase A2, group IVC (cytosolic, calcium-independent) protein_coding Danio_rerio
ENSMUSG00000033847 Pla2g4c phospholipase A2, group IVC (cytosolic, calcium-independent) protein_coding Mus_musculus

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