C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IMP (inosine 5'-monophosphate) dehydrogenase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106348 IMPDH1 9606 - 7:128392277-128410252 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000338791 IMPDH1-005 128392277-128410252 protein_coding
  ENST00000348127 IMPDH1-002 128392301-128409982 protein_coding
  ENST00000354269 IMPDH1-001 128392278-128409982 protein_coding
  ENST00000419067 IMPDH1-003 128392277-128409901 protein_coding
  ENST00000460045 IMPDH1-015 128394275-128395171 retained_intron
  ENST00000468842 IMPDH1-011 128398490-128400685 retained_intron
  ENST00000469328 IMPDH1-013 128392277-128405865 nonsense_mediated_decay
  ENST00000470772 IMPDH1-016 128392739-128405942 protein_coding
  ENST00000473463 IMPDH1-006 128400843-128409982 nonsense_mediated_decay
  ENST00000480861 IMPDH1-009 128392850-128405942 protein_coding
  ENST00000484496 IMPDH1-014 128392277-128409486 nonsense_mediated_decay
  ENST00000489263 IMPDH1-012 128400135-128409947 protein_coding
  ENST00000491376 IMPDH1-004 128400817-128409982 retained_intron
  ENST00000496200 IMPDH1-008 128392278-128405948 protein_coding
  ENST00000496487 IMPDH1-010 128400672-128405939 retained_intron
  ENST00000497868 IMPDH1-007 128398414-128409986 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000348127ENST00000354269ENST00000419067ENST00000460045ENST00000469328ENST00000470772ENST00000473463ENST00000480861ENST00000496200ENST00000496487ENST00000497868
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000348127 18.005±0.00 8.560±0.00 N/A 1.949±0.00 5.785±4.06 12.042±0.00 3.819±0.00 2.258±0.00 0.795±0.48 9.734±0.00 N/A 18.644±14.66 6.503±3.20 4.507±0.00
ENST00000354269 N/A 2.582±0.00 N/A N/A N/A 2.182±0.00 N/A N/A N/A N/A N/A 2.922±0.00 4.272±0.00 N/A
ENST00000419067 N/A N/A N/A N/A N/A N/A 1.065±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000460045 N/A N/A 0.243±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000469328 N/A 2.951±0.00 N/A N/A N/A N/A N/A N/A 0.994±0.00 N/A N/A N/A N/A N/A
ENST00000470772 8.764±0.00 N/A N/A 1.182±0.00 5.197±0.00 N/A N/A 3.223±0.00 N/A 1.079±0.00 0.354±0.00 15.749±0.00 N/A 2.911±0.00
ENST00000473463 N/A N/A N/A 2.632±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000480861 N/A N/A N/A 0.462±0.00 1.529±0.00 0.890±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000496200 9.514±0.00 3.592±0.00 0.139±0.00 1.603±1.15 4.506±0.00 N/A N/A 3.148±2.73 0.531±0.00 N/A 0.502±0.00 N/A N/A 6.549±0.00
ENST00000496487 N/A N/A 0.440±0.00 N/A N/A N/A N/A N/A N/A N/A 2.846±0.00 4.197±0.00 N/A N/A
ENST00000497868 N/A N/A N/A N/A 2.056±0.00 N/A N/A N/A N/A N/A 0.363±0.00 1.410±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001OE CIL_0001OE_0001 CGP 7:128350325-128410252

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IDA nucleic acid binding
GO:0003677 IDA DNA binding
GO:0003723 IEA RNA binding
GO:0003824 IEA catalytic activity
GO:0003938 IEA IMP dehydrogenase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006164 IEA purine nucleotide biosynthetic process
GO:0006177 IEA GMP biosynthetic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0016491 IEA oxidoreductase activity
GO:0018580 IEA nitronate monooxygenase activity
GO:0030554 IEA adenyl nucleotide binding
GO:0044281 TAS small molecule metabolic process
GO:0046651 IEA lymphocyte proliferation
GO:0046872 IEA metal ion binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029524 impdh1b inosine 5'-phosphate dehydrogenase 1b protein_coding Danio_rerio
ENSDARG00000042336 impdh1a inosine 5'-phosphate dehydrogenase 1a protein_coding Danio_rerio
ENSMUSG00000003500 Impdh1 inosine 5'-phosphate dehydrogenase 1 protein_coding Mus_musculus

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