C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aryl hydrocarbon receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106546 AHR 9606 + 7:17298622-17346152 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000242057 AHR-002 17298622-17346150 protein_coding
  ENST00000463496 AHR-001 17298683-17346152 nonsense_mediated_decay
  ENST00000475440 AHR-003 17329858-17333950 processed_transcript
  ENST00000481944 AHR-004 17334910-17336075 processed_transcript
  ENST00000492120 AHR-005 17335645-17339527 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000242057ENST00000463496ENST00000492120
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000242057 11.740±0.00 11.921±0.00 N/A 1.974±0.85 8.341±2.17 7.777±3.90 3.435±1.73 7.206±0.00 5.731±0.08 19.139±0.00 1.038±0.00 7.547±2.74 4.860±0.90 3.328±1.97
ENST00000463496 3.441±0.00 N/A 0.511±0.00 1.072±0.35 10.655±0.00 5.155±0.00 1.947±0.00 3.833±0.00 12.885±0.00 14.633±0.00 0.172±0.07 6.727±3.41 1.113±0.00 1.276±0.00
ENST00000492120 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.650±0.00 18.643±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001568 NAS blood vessel development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005667 TAS transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006355 IDA:IEA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006805 TAS xenobiotic metabolic process
GO:0006915 TAS apoptotic process
GO:0007049 IEA cell cycle
GO:0007165 IEA signal transduction
GO:0008134 IPI transcription factor binding
GO:0009410 IDA response to xenobiotic stimulus
GO:0009636 IDA response to toxic substance
GO:0010468 IDA regulation of gene expression
GO:0030522 IDA intracellular receptor signaling pathway
GO:0030850 IEA prostate gland development
GO:0030888 IDA regulation of B cell proliferation
GO:0032922 ISS circadian regulation of gene expression
GO:0034752 TAS cytosolic aryl hydrocarbon receptor complex
GO:0035326 IDA enhancer binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045899 IEA positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0046982 TAS protein heterodimerization activity
GO:0046983 TAS:IEA protein dimerization activity
GO:0048608 IEA reproductive structure development
GO:0048732 IEA gland development
GO:0051879 IDA Hsp90 protein binding
GO:0070888 ISS E-box binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020046 ahr1a aryl hydrocarbon receptor 1a protein_coding Danio_rerio
ENSMUSG00000019256 Ahr aryl-hydrocarbon receptor protein_coding Mus_musculus

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