C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leucine zipper, putative tumor suppressor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107816 LZTS2 9606 + 10:100996618-101007836 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370220 LZTS2-001 100999476-101007836 protein_coding
  ENST00000370223 LZTS2-002 100997072-101007836 protein_coding
  ENST00000426584 LZTS2-004 100996618-101003818 protein_coding
  ENST00000429732 LZTS2-007 100998348-101003694 protein_coding
  ENST00000454422 LZTS2-006 100999853-101003760 protein_coding
  ENST00000481129 LZTS2-008 100998687-101002946 protein_coding
  ENST00000489526 LZTS2-005 100997114-101003177 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370220ENST00000370223ENST00000429732ENST00000454422
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370220 N/A N/A 0.546±0.00 1.760±0.00 N/A 0.151±0.00 0.238±0.00 0.134±0.00 N/A 0.286±0.00 0.488±0.00 0.466±0.00 N/A N/A
ENST00000370223 8.206±0.00 23.578±0.00 N/A 12.637±0.00 14.367±0.00 14.945±0.00 3.679±0.00 10.303±0.00 1.491±0.00 10.137±0.00 N/A 8.508±5.34 27.284±0.00 18.919±6.74
ENST00000429732 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.175±0.00 N/A N/A N/A N/A
ENST00000454422 N/A N/A N/A N/A N/A 1.304±0.00 N/A N/A 1.407±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BD CIL_0008BD_0001 VISTA 10:100486833-101088338
CIL_0007U1 CIL_0007U1_0001 VISTA 10:100491715-101092615
CIL_000940 CIL_000940_0001 VISTA 10:100919065-101519843
CIL_0005ND CIL_0005ND_0001 CGP 10:100987367-101007836
CIL_0001C9 CIL_0001C9_0002 CGP 10:100996618-101031157

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000910 IEA cytokinesis
GO:0001822 IEA kidney development
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005813 IEA centrosome
GO:0005874 IEA microtubule
GO:0007067 IEA mitotic nuclear division
GO:0008285 IEA negative regulation of cell proliferation
GO:0016055 IEA Wnt signaling pathway
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0030496 IEA midbody
GO:0051013 IEA microtubule severing
GO:0051168 IEA nuclear export
GO:0051255 IEA spindle midzone assembly
GO:0072001 IEA renal system development
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:1900181 IEA negative regulation of protein localization to nucleus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074597 lzts2a leucine zipper, putative tumor suppressor 2a protein_coding Danio_rerio
ENSDARG00000077207 lzts2b leucine zipper, putative tumor suppressor 2b protein_coding Danio_rerio
ENSMUSG00000035342 Lzts2 leucine zipper, putative tumor suppressor 2 protein_coding Mus_musculus

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