C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leucine zipper, putative tumor suppressor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035342 Lzts2 10090 + 19:45015176-45027104 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039016 Lzts2-201 45015176-45027104 protein_coding
  ENSMUST00000178087 Lzts2-202 45018135-45027104 protein_coding
  ENSMUST00000179108 Lzts2-203 45015210-45027104 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039016ENSMUST00000178087ENSMUST00000179108
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039016 8.954±1.69 10.928±1.45 6.889±0.10 N/A 10.311±2.49 16.139±4.37 2.844±0.22 5.094±1.41 1.462±0.75 7.156±0.26 2.444±0.00 17.425±2.62 11.266±5.63 2.816±0.55
ENSMUST00000178087 23.971±7.48 62.863±4.33 23.497±1.53 13.136±2.04 21.657±11.84 26.934±5.84 6.990±1.07 9.560±2.34 2.438±1.56 22.982±1.86 5.863±1.30 47.418±9.79 22.984±15.21 9.310±3.86
ENSMUST00000179108 6.610±0.00 N/A N/A 4.655±0.00 6.967±0.71 10.684±1.34 2.409±0.00 4.253±0.94 1.230±0.48 5.798±0.00 2.405±0.21 15.323±7.32 17.206±13.07 0.882±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BD CIL_0008BD_0002 VISTA 19:44496521-45098014
CIL_0007U1 CIL_0007U1_0002 VISTA 19:44501251-45102539
CIL_000940 CIL_000940_0002 VISTA 19:44925545-45526320
CIL_0005ND CIL_0005ND_0002 CGP 19:45006558-45027104
CIL_0001C9 CIL_0001C9_0003 CGP 19:45015176-45046614

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000910 IEA cytokinesis
GO:0001822 IMP kidney development
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005813 IEA centrosome
GO:0005874 IEA microtubule
GO:0007067 IEA mitotic nuclear division
GO:0008285 IMP negative regulation of cell proliferation
GO:0016055 IGI Wnt signaling pathway
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0030496 IEA midbody
GO:0051013 IEA microtubule severing
GO:0051168 IEA nuclear export
GO:0051255 IEA spindle midzone assembly
GO:0072001 IMP renal system development
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway
GO:1900181 IMP negative regulation of protein localization to nucleus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074597 lzts2a leucine zipper, putative tumor suppressor 2a protein_coding Danio_rerio
ENSDARG00000077207 lzts2b leucine zipper, putative tumor suppressor 2b protein_coding Danio_rerio
ENSG00000107816 LZTS2 leucine zipper, putative tumor suppressor 2 protein_coding Homo_sapiens

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