C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: paired-like homeodomain 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107859 PITX3 9606 - 10:102230186-102241474 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370002 PITX3-001 102230186-102241474 protein_coding
  ENST00000539804 PITX3-201 102230186-102232083 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastHeartLungMusclePlacentaTestisENST00000370002ENST00000539804
Transcript ID Adipose Breast Heart Lung Muscle Placenta Testis
ENST00000370002 N/A N/A 0.517±0.00 0.289±0.00 9.388±0.00 N/A 0.244±0.00
ENST00000539804 0.160±0.00 0.317±0.00 1.203±0.00 N/A 1.690±0.00 0.095±0.00 0.368±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005WH CIL_0005WH_0001 CGP 10:102226328-102241474
CIL_0005WI CIL_0005WI_0001 CGP 10:102230186-102382899

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0002088 ISS lens development in camera-type eye
GO:0002089 ISS lens morphogenesis in camera-type eye
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0007626 IEA locomotory behavior
GO:0009887 TAS organ morphogenesis
GO:0010468 IEA regulation of gene expression
GO:0030901 ISS midbrain development
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048666 IEA neuron development
GO:0070306 IEA lens fiber cell differentiation
GO:0071542 ISS dopaminergic neuron differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070069 pitx3 paired-like homeodomain transcription factor 3 protein_coding Danio_rerio
ENSMUSG00000025229 Pitx3 paired-like homeodomain transcription factor 3 protein_coding Mus_musculus

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