C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuralized E3 ubiquitin protein ligase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107954 NEURL1 9606 + 10:103493979-103592552 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000369780 NEURL1-001 103493979-103592552 protein_coding
  ENST00000437579 NEURL1-002 103555232-103571822 protein_coding
  ENST00000455386 NEURL1-003 103558085-103571722 protein_coding
  ENST00000465048 NEURL1-004 103571677-103577902 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369780ENST00000437579ENST00000455386ENST00000465048
Transcript ID Adipose Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369780 N/A 5.039±2.69 N/A 0.054±0.00 0.389±0.37 0.051±0.00 0.077±0.00 N/A 0.994±0.65 1.999±0.88 3.230±1.62
ENST00000437579 N/A N/A 0.489±0.00 N/A 0.106±0.00 1.672±0.00 0.626±0.00 6.460±0.00 N/A N/A N/A
ENST00000455386 0.180±0.00 N/A N/A 0.136±0.00 N/A N/A N/A N/A 0.695±0.00 N/A N/A
ENST00000465048 N/A N/A 1.083±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006T9 CIL_0006T9_0001 CGP 10:103493979-103855543

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006417 IEA regulation of translation
GO:0006513 ISS protein monoubiquitination
GO:0007219 IEA Notch signaling pathway
GO:0007288 IEA sperm axoneme assembly
GO:0007399 TAS nervous system development
GO:0007595 IEA lactation
GO:0008270 IEA zinc ion binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0014069 ISS postsynaptic density
GO:0016874 IEA ligase activity
GO:0030054 IEA cell junction
GO:0030317 IEA sperm motility
GO:0043065 IDA positive regulation of apoptotic process
GO:0043197 ISS dendritic spine
GO:0043204 ISS perikaryon
GO:0045183 ISS translation factor activity, non-nucleic acid binding
GO:0045211 IEA postsynaptic membrane
GO:0045741 IEA positive regulation of epidermal growth factor-activated receptor activity
GO:0045746 IDA negative regulation of Notch signaling pathway
GO:0048170 ISS positive regulation of long-term neuronal synaptic plasticity
GO:0051491 ISS positive regulation of filopodium assembly
GO:0060999 ISS positive regulation of dendritic spine development
GO:0071230 ISS cellular response to amino acid stimulus
GO:0090129 ISS positive regulation of synapse maturation
GO:0097440 ISS apical dendrite

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069438 neurl1aa neuralized homolog 1Aa (Drosophila) protein_coding Danio_rerio
ENSMUSG00000006435 Neurl1a neuralized homolog 1A (Drosophila) protein_coding Mus_musculus

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